Re: Re: When you swallow your MTX....

[Guest guest]

Amy,

Is that folic acid you are taking prescription or OTC? I can't imagine

taking 4 mg of folic a day. Isn't the normal or average prescribed dose 1 mg a

day with MTX?

Thanks,

Heidi

To those who believe, no explanation is necessary; to those who dont, no

explanation is possible

In a message dated 5/16/2008 1:37:53 P.M. Eastern Daylight Time,

cleo2557@... writes:

I've never had a problem with it, but I am taking 4 folic acid pills per

day. Maybe that does make the difference. I believe MTX is also available in

an injectable form. A friend of mine was injecting it for years. I don't

know whether that would make a difference, but it might be worth asking your

doctor.

Amy

[ ] Re: When you swallow your MTX....

I had a few that went away quickly, then I started getting more

sores/blisters in my mouth. When I told my doctor she upped my folic

acid.

>

> Do you ever get a burning in your throat and an instant mouth sore?

This is my second week of treatment and last week I thought perhaps I

had something with too much acid for dinner but the same thing

happened tonight! Almost instantaneous! It went away rather quickly

last week.

>

> Just wondering if anyone else experiences this! Thanks!

>

>

>

> *~ Kami ~*

>

>

>

>

> [Non-text portions of this message have been removed]

>

[Non-text portions of this message have been removed]

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[Guest guest]

yes there is, but i don't know regarding the difference in dosage. i

suppose that's the difference...LOL, i just thougth 4mg a day seems to be too

much.

that's what made me ask about the OTC. trying to learn about it myself. I

remember asking my rheumy though if we should increase me to 2 mg a day. He

stated no, because too much can hinder the effectiveness of MTX.

Heidi

To those who believe, no explanation is necessary; to those who dont, no

explanation is possible

In a message dated 5/16/2008 3:27:37 P.M. Eastern Daylight Time,

jrmcf2@... writes:

Is there a difference between prescription and OTC Folic Acid?

Jere

[Non-text portions of this message have been removed]

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[Guest guest]

I've never had a problem with it, but I am taking 4 folic acid pills per day. 

Maybe that does make the difference.  I believe MTX is also available in an

injectable form.  A friend of mine was injecting it for years.  I don't know

whether that would make a difference, but it might be worth asking your doctor.

Amy

[ ] Re: When you swallow your MTX....

I had a few that went away quickly, then I started getting more

sores/blisters in my mouth. When I told my doctor she upped my folic

acid.

>

> Do you ever get a burning in your throat and an instant mouth sore?

This is my second week of treatment and last week I thought perhaps I

had something with too much acid for dinner but the same thing

happened tonight! Almost instantaneous! It went away rather quickly

last week.

>

> Just wondering if anyone else experiences this! Thanks!

>

>

>

> *~ Kami ~*

>

>

>

>

>

[Guest guest]

I take 1mg morning and night, 7 days a week, perscription. mary in pa

[ ] Re: When you swallow your MTX....

I had a few that went away quickly, then I started getting more

sores/blisters in my mouth. When I told my doctor she upped my folic

acid.

>

> Do you ever get a burning in your throat and an instant mouth sore?

This is my second week of treatment and last week I thought perhaps I

had something with too much acid for dinner but the same thing

happened tonight! Almost instantaneous! It went away rather quickly

last week.

>

> Just wondering if anyone else experiences this! Thanks!

>

>

>

> *~ Kami ~*

>

>

>

>

>

[Guest guest]

Is there a difference between prescription and OTC Folic Acid?

Jere

[Guest guest]

Hi everyone,

I take 3mg of Folic Acid a day -- except the day I take my MTX. It is a

Rx. It costs $7.99 at the pharmacy (less than my $10 co-pay).

Steph in VA

[Guest guest]

hi steph i take the mtx the same way! does it help you, the mtx? god

bless,melyndagamez 5/17/08 5:12p.m.central

[ ] Re: Re: When you swallow your MTX....

Hi everyone,

      I take 3mg of Folic Acid a day -- except the day I take my MTX. It is a

Rx. It costs $7.99 at the pharmacy (less than my $10 co-pay).

 

  Steph in VA

     

[Guest guest]

The big difference is in the amount per pill. Most OTC's are 400 mgs-scripts

are 1000mgs

Jere McFarland <jrmcf2@...> wrote: Is there a difference between

prescription and OTC Folic Acid?

Jere

[Guest guest]

Heidi,

My folic acid is prescribed.  I am taking 4 (1 mg) tablets per day.  Maybe the

folic acid dosage depends on the MTX dosage.  I take 5 (25 mg) tablets once a

week.  I do know that several years ago my folic acid dosage was increased as a

result of these little blistery-type things (very hard to describe) that I

developed on my fingers (I think because of my high uric acid level). 

Increasing it took care of the problem.  I should probably tell you that I also

suffer from Gout, and the folic acid is part of the treatment for that as well

as the RA.

Don't know whether any of this helps.

Amy

[ ] Re: When you swallow your MTX....

I had a few that went away quickly, then I started getting more

sores/blisters in my mouth. When I told my doctor she upped my folic

acid.

>

> Do you ever get a burning in your throat and an instant mouth sore?

This is my second week of treatment and last week I thought perhaps I

had something with too much acid for dinner but the same thing

happened tonight! Almost instantaneous! It went away rather quickly

last week.

>

> Just wondering if anyone else experiences this! Thanks!

>

>

>

> *~ Kami ~*

>

>

>

>

>

[Guest guest]

Hi,

Apologies if this mail has some extra characters, changes seem to happen when

sent UK/States.

This is very  complicated and confusing.I did send a previous post you could

probably find on the subject....

In Britain we would say 400 micrograms .That is just less tha 500 micrograms

(the m you may notice is written with a little tail, it is a Greek small m

which makes all the difference) This is a very small dose as given in vitamin

supplements, supposed to equate with a good dietary intake and no more. 500

micrograms is just half a milligram. So usually about ten times the OTC dose is

used in therapy with methotrexate by the doctor. The aim is as follows.

When used with methotrexate folic acid should be prescribed by the doctor

at a higher dose to hopefully counteract some but not all side effects of

Methotrexate on healthy dividing cells of mouth gut, skin etc. (When they slow

down how fast they replace themselves mouth ulcers etc can occur)

Of course that is the way that the methotrexate is going to work on the

overactive inflammatory cells so it is a risks/ benefits scenario and often a

fine balance for each individual. Evidence is that the precise dose can be

tailored to the patient, doses range from between 1mg daily, except day of MTX,

or 5mg on day after MTX  (this commonly used in UK) to higher doses.

The 24 hour after taking MTX is usually kept clear of folic acid, so in

theory the desired MTX effect on the immune system can be unimpaired. Folic

acid 10mg daily or even higher have been used on other days of the week,and

although this would be uncommon in uncomplicated rheumatoid.it is

perfectly safe.

Best wishes

retired doc in UK, friend of RA sufferer

Re: [ ] Re: When you swallow your MTX....

The big difference is in the amount per pill. Most OTC's are 400 mgs-scripts are

1000mgs

Jere McFarland <jrmcf2@...> wrote: Is there a difference between

prescription and OTC Folic Acid?

Jere

[Guest guest]

Amy,

I would be very interested to learn more about the little blistery-type things

you were talking about. I've had blistery type things on my hands for the last

couple of months. Off and on. No idea what they are. I would like to hear of

your experience if you don't mind talking about it.

Thank you,

Phyllis

[ ] Re: When you swallow your MTX....

I had a few that went away quickly, then I started getting more

sores/blisters in my mouth. When I told my doctor she upped my folic

acid.

>

> Do you ever get a burning in your throat and an instant mouth sore?

This is my second week of treatment and last week I thought perhaps I

had something with too much acid for dinner but the same thing

happened tonight! Almost instantaneous! It went away rather quickly

last week.

>

> Just wondering if anyone else experiences this! Thanks!

>

>

>

> *~ Kami ~*

>

>

>

>

>