Guest guest Posted May 22, 2008 Report Share Posted May 22, 2008 My rheumy told me it takes up to six weeks for the full effects of the methotrexate to start working. At three weeks i started to feel better i take four pills but was also on prednisone. I am now of off the prednisone Am really achy again. I used to have the bone chilling cold but not anymore since the metho. Hopes this helps. Jolene In a message dated 5/22/2008 7:47:25 P.M. Eastern Daylight Time, thea7441@... writes: Okay everyone, I take 7.5 mg of methotrexate once a week, and have been for two weeks now. For some reason, it wipes me out for a couple of days. I'm tired and COLD, so cold that even air hitting my skin when I walk chills me badly. What's going on? Is it the mtx? Also, I was told that plaquinil does not have any therapeutic effects for a couple of months, but I swear it worked in a couple of days for me. Is that weird, or normal? I know it worked because the pain in my hands was severe, and when I took the plaquinil, four days later the pain lessened considerably. Then, my rheumatologist put me on methotrexate and said to not take the plaquinil. Well, after a few days, my hands and wrists were in incredible pain, so I started the plaquinil again - three days later the pain subsided. In short, plaquinil must have a quicker therapeutic effect, right? What does everyone else think? Also, is it normal to be wiped out and cold after taking MTX, and will this go away? Thank you, Rosen ************************<WBR>**Get trade secrets for amazing burgers. Wat Tyler Florence " on AOL Food. (_http://food.http://food.<Whttp://fohttp:// & ??<WBR>NCID=aolfo?<WBR>NCI_ (http://food.aol.com/tyler-florence?video=4 & ?NCID=aolfod00030000000002) ) [Non-text portions of this message have been removed] **************Get trade secrets for amazing burgers. Watch " Cooking with Tyler Florence " on AOL Food. (http://food.aol.com/tyler-florence?video=4 & ?NCID=aolfod00030000000002) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 22, 2008 Report Share Posted May 22, 2008 Plaquenil took me about 6 months to be somewhat effective. later, it was not enough on its own so we added 3000mgs of sulfasalazine. I do notice if I ever miss one dose of it, I feel increased pain immediately thea7441@... wrote: Okay everyone, I take 7.5 mg of methotrexate once a week, and have been for two weeks now. For some reason, it wipes me out for a couple of days. I'm tired and COLD, so cold that even air hitting my skin when I walk chills me badly. What's going on? Is it the mtx? Also, I was told that plaquinil does not have any therapeutic effects for a couple of months, but I swear it worked in a couple of days for me. Is that weird, or normal? I know it worked because the pain in my hands was severe, and when I took the plaquinil, four days later the pain lessened considerably. Then, my rheumatologist put me on methotrexate and said to not take the plaquinil. Well, after a few days, my hands and wrists were in incredible pain, so I started the plaquinil again - three days later the pain subsided. In short, plaquinil must have a quicker therapeutic effect, right? What does everyone else think? Also, is it normal to be wiped out and cold after taking MTX, and will this go away? Thank you, Rosen **************Get trade secrets for amazing burgers. Watch " Cooking with Tyler Florence " on AOL Food. (http://food.aol.com/tyler-florence?video=4 & ?NCID=aolfod00030000000002) Quote Link to comment Share on other sites More sharing options...
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