INFO - MTX and getting pregnant

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s Hopkins Arthritis Center

Last update: 02:25 PM Thursday, April 26, 2007

Methotrexate and getting pregnant

My husband takes methotrexate for dermatomyositis. We have 1 child we

conceived befoer he got sick. He has been on methotrexate for 2 years.

How long does he have to stop before we can try to conceive? Will this

affect his fertility?

Methotrexate should not affect his fertility. In men, methotrexate

needs to be stopped 90 days prior to attempting pregnancy. Women need

to be off 2 ovulatory cycles (2 menstral periods). Thus is due to the

small possibility of birth defects associated with methotrexate use

during conception and pregnancy.

http://www.hopkins-arthritis.org/ask-the-expert/treatment-020003/methotrexate-an\

d-getting-pregn-877.html

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Not an MD