Sensitivity to hydrolyzed wheat protein in facial soap

[Guest guest]

We often see LEAP clients topically reactive to MRT reactive

chemicals/colors/foods. This interesting abstract helps confirm that even soap

can

create problems in sensitive clients. I wonder about the application of this to

celiac clients - but clearly, celiac isn't about a histamine or igE

reaction.

Jan Patenaude

The sensitivity and clinical course of patients with wheat-dependent

exercise-induced anaphylaxis sensitized to hydrolyzed wheat protein in facial

soap.

An increasing number of patients with wheat-dependent exercise-induced

anaphylaxis (WDEIA), developed during or after using hydrolyzed wheat protein

(HWP)-containing soap (HWP-WDEIA), were reported in Japan. This study

attempted to clarify the relation between WDEIA and HWP-containing soap and

their prognosis. Among 36 patients with WDEIA, 30 patients had used only one

type of HWP-soap. The patients with HWP-WDEIA were mainly women and had

developed facial symptoms and angioedema. They suffered from blood pressure

reductions less frequently than patients with conventional WDEIA. The levels of

glutens-specific IgE were higher than those of omega-5 gliadin in patients

with HWP-WDEIA (p<0.05). All patients with HWP-WDEIA were positive against

HWP in histamine release test. Among the conventional wheat antigens,

glutenins induced highest histamine release from basophils of patients with

HWP-WDEIA. The sensitivities of patients against glutens and glutenins were

reduced over months along with the discontinuance o f HWP-soap. The

development of HWP-WDEIA is associated with the use of HWP-soap. The

sensitivities to

HWP that cross reacts with non-processed wheat may be reduced or possibly

cured after the discontinuation of HWP-soap.

Hiragun M, Ishii K, Hiragun T, Shindo H, Mihara S, Matsuo H, Hide M.

The sensitivity and clinical course of patients with wheat-dependent

exercise-induced anaphylaxis sensitized to hydrolyzed wheat protein in facial

soap. [Japanese]

Arerugi 2011 Dec;60(12):1630-1640

Jan Patenaude, RD, CLT

Director of Medical Nutrition

Signet Diagnostic Corp.

Telecommuting Nationwide

(Mountain Time)

Fax:

DineRight4@...

Certified LEAP Therapist and specialist in food sensitivity for IBS,

migraine, fibromyalgia and multiple inflammatory conditions. Co-author of the

Certified LEAP Therapist (CLT) Training Course.

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