RESEARCH - Tailor-made therapy in RA: fact or fiction?

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Isr Med Assoc J. 2008 Feb;10(2):139-41.

Tailor-made therapy in rheumatoid arthritis: fact or fiction?

Haroon N, Misra R, Aggarwal A.

Department of Clinical Immunology, Sanjay Gandhi Postgraduate

Institute of Medical Sciences, Lucknow, India.

There has been a paradigm shift in the treatment of rheumatoid

arthritis in recent years. Early and aggressive treatment with good

control of disease activity has improved the prognosis of the disease,

however, there is significant variability in the response of patients

to different therapeutic agents. Hence it is essential to find the

predictors of response to a drug at baseline so that we can avoid the

delay in achieving remission and improve the outcome. Here we review

the literature on available predictors for treatment response in

general and specifically for methotrexate and biological agents. We

also look at specific scores or indices that can help predict the

response in individual patients.

" Tailor-made therapy in rheumatoid arthritis: fact or ficiton? " :

http://www.ima.org.il/imaj/ar08feb-11.pdf

(full article)

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Not an MD