Guest guest Posted September 29, 2008 Report Share Posted September 29, 2008 All. I don't know if this has been discussed here before but I wonder if others or are using Enbrel or the like aren't making (getting relief) for a full 7 days. I have been on Enbrel just over a year and the last few weeks I have noticed that 2 days before I am due for my injection, my most involved joint, my left hip, become painful and I have pain and limp for two days. I take my injections Tuesday morning around 7am. My joint pain is usally gone when I wake up on Wednesday morning. By the following Sunday or Monday, my hip is killing me. For the first year, this was not the case so I wonder if I am developing antibodies that are rendering the Enbrel less and less effective as time goes on. Has this happened to anyone else? Is this considered therapeutic failure? Is it time to change drugs? ...Add MTX? Any thoughts or hearing about your experience would be much appreciated. Thanks in advance. Diane Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 29, 2008 Report Share Posted September 29, 2008 are you taking 50 mg? why not take 2 25 mg shots a week. my friend does this. monique Quote Link to comment Share on other sites More sharing options...
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