Re: MTX-when did side effects kick in?

[Guest guest]

In a message dated 10/5/2008 5:58:46 P.M. Central Daylight Time,

ldydewinter@... writes:

My doctor gave me MTX in pill form, which I took on Thursday. I have

to say, I feel incredible! The only pain I feel now is a slight ache

in my arm. But everyone here seems to have terrible side effects from

MTX. When did these start? I took MTX about eleven years ago when it

was still only used for leukemia (which I had). I don't remember having

any specific side effects from just MTX, but I had side effects from

alot of the other drugs at the time. I'm really hoping I bypassed any

nasty side effects and can get on with my life. I haven't felt this

good in a long time.

in TN

You are lucky. I started on 6 Mtx on a Monday. I started feeling nauseated

and more tired than usual -- like I was getting the flu. I expected it to last

a day, but on the third day I was still feeling sick. After a couple of

week, the RA doc reduced it to 4 pills a week and added Arava.

I still feel sick each week and now I've started to get terrible fatigue on

Sunday -- the day before I take them. Maybe Mtx and you just mesh.

dd

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[Guest guest]

,

The mtx pills gives me lots of problems. When I take them, I have

horrible diarrhea and nausea. I would start taking the pills at night

before bed, and I would wake up throwing up in my sleep. Also,

horrible fatigue that just leaves me in bed.

I've switched to the injection, and I am doing much better, without all

the problems.

Glad to hear your doing great on the med, and you can get to feeling

better, Tawny

--- In , " ldydewinter04 " <ldydewinter@...>

wrote:

>

> My doctor gave me MTX in pill form, which I took on Thursday. I have

> to say, I feel incredible! The only pain I feel now is a slight ache

> in my arm. But everyone here seems to have terrible side effects from

> MTX. When did these start? I took MTX about eleven years ago when it

> was still only used for leukemia (which I had). I don't remember

having

> any specific side effects from just MTX, but I had side effects from

> alot of the other drugs at the time. I'm really hoping I bypassed any

> nasty side effects and can get on with my life. I haven't felt this

> good in a long time.

> in TN

>

[Guest guest]

I like Tawny too mine pills at bedtime. I would have nausea,

diarrhea, headache, horrible fatigue and dizziness if I rolled over in

bed during the nite. This would last until day six after the pills

and of course on day 7 you take the pills again.

I also had mouth and eye sores but it took about 3 weeks for that to

happen. I switched to injections and did not get any real change in

the side effects...actually they began quicker...before I could even

get to sleep. So I would take mine on friday and be green all

weekend...and spend most of the week on the cold bathroom floor.

It just did not work for me...not matter how the doc adjusted the

dosage. I was just too sensitive for it. I was also on 5 mg folic

acid and leukovorin on MTX day.

If you get no side effects you are lucky...good luck I hope it

continues that way.

Toni

--- In , " ldydewinter04 " <ldydewinter@...>

wrote:

>

> My doctor gave me MTX in pill form, which I took on Thursday. I have

> to say, I feel incredible! The only pain I feel now is a slight ache

> in my arm. But everyone here seems to have terrible side effects from

> MTX. When did these start? I took MTX about eleven years ago when it

> was still only used for leukemia (which I had). I don't remember having

> any specific side effects from just MTX, but I had side effects from

> alot of the other drugs at the time. I'm really hoping I bypassed any

> nasty side effects and can get on with my life. I haven't felt this

> good in a long time.

> in TN

>

[Guest guest]

,

I still take MTX in pill form. I don't have servere reactions from

them. I do have extreme fatigue the next day and some the second

day. I know that I do get some benefit with it helping my pain.

I hope it continues to help this much.

Shirley

>

> >

> > My doctor gave me MTX in pill form, which I took on Thursday. I

have

> > to say, I feel incredible! The only pain I feel now is a slight

ache

> > in my arm. But everyone here seems to have terrible side

effects from

> > MTX. When did these start? I took MTX about eleven years ago

when it

> > was still only used for leukemia (which I had). I don't remember

having

> > any specific side effects from just MTX, but I had side effects

from

> > alot of the other drugs at the time. I'm really hoping I

bypassed any

> > nasty side effects and can get on with my life. I haven't felt

this

> > good in a long time.

> > in TN

> >

>

[Guest guest]

,

I just took my third weekly dose last night. For me, the side effects

seem to kick in just about 24 hours later. I fortunately slept pretty

well last night which for me and the 20MG of Pred. daily is a bit of a

surprise and today, outside of fatigue and hangover like feeling,

wasn't too bad. But just about the point where it's about 24 hours

since taking the dose, I have a headache and nausea. This happened

last week too. Hoping tomorrow morning is better and this doesn't

uplet my sleep.

Bob

--- In , " ldydewinter04 " <ldydewinter@...>

wrote:

>

> My doctor gave me MTX in pill form, which I took on Thursday. I have

> to say, I feel incredible! The only pain I feel now is a slight ache

> in my arm. But everyone here seems to have terrible side effects

from

> MTX. When did these start? I took MTX about eleven years ago when

it

> was still only used for leukemia (which I had). I don't remember

having

> any specific side effects from just MTX, but I had side effects from

> alot of the other drugs at the time. I'm really hoping I bypassed any

> nasty side effects and can get on with my life. I haven't felt this

> good in a long time.

> in TN

>

[Guest guest]

I just have to post that it drives me crazy that so many from this group give

the impression that you are going to have side effects if you take MTX and it's

just not true for the majority of people out there on it. I can't imagine how

scared someone recently diagnosed with RA must feel. I have been on it for 9

years now and my only side effect is slight thinning of my hair on top, slight.

It gave me my life back. MTX is the standard of care for RA, don't be afraid to

give it a try. I know quite a few people on it presently and I have had a

discussion with my RA doc about how many of his patients on it do well. in

PA

-------------- Original message --------------

From: dgd301@...

In a message dated 10/5/2008 5:58:46 P.M. Central Daylight Time,

ldydewinter@... writes:

My doctor gave me MTX in pill form, which I took on Thursday. I have

to say, I feel incredible! The only pain I feel now is a slight ache

in my arm. But everyone here seems to have terrible side effects from

MTX. When did these start? I took MTX about eleven years ago when it

was still only used for leukemia (which I had). I don't remember having

any specific side effects from just MTX, but I had side effects from

alot of the other drugs at the time. I'm really hoping I bypassed any

nasty side effects and can get on with my life. I haven't felt this

good in a long time.

in TN

You are lucky. I started on 6 Mtx on a Monday. I started feeling nauseated

and more tired than usual -- like I was getting the flu. I expected it to last

a day, but on the third day I was still feeling sick. After a couple of

week, the RA doc reduced it to 4 pills a week and added Arava.

I still feel sick each week and now I've started to get terrible fatigue on

Sunday -- the day before I take them. Maybe Mtx and you just mesh.

dd

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[Guest guest]

Hi and all, thanks for posting this,. i was getting pretty

scared reading some of the posts re mtx. I'm so glad to read that

you are doing well with it.

I do not have a diagnosis yet. I am going to the rheumy for first

time this Tuesday. My feet and hands hurt and are stiff, and my

ankles and knees are swollen. I cant get up and down steps anymore,

and i can barely walk. I struggle to get up out of chairs because

of my knees. I cant get my groceries or walk my dog. And i am only

51. This has started near the beginning of 2008 and continually

getting worse, especially in the last couple months with my knees

swelling.

So i hope the rheumy can prescribe some med for me that will help.

Do you take MTX pills or injections?

Jacky in Canada

>

> I just have to post that it drives me crazy that so many from this

group give the impression that you are going to have side effects if

you take MTX and it's just not true for the majority of people out

there on it. I can't imagine how scared someone recently diagnosed

with RA must feel. I have been on it for 9 years now and my only

side effect is slight thinning of my hair on top, slight. It gave me

my life back. MTX is the standard of care for RA, don't be afraid to

give it a try. I know quite a few people on it presently and I have

had a discussion with my RA doc about how many of his patients on it

do well. in PA

>

> -------------- Original message --------------

> From: dgd301@...

>

>

> In a message dated 10/5/2008 5:58:46 P.M. Central Daylight Time,

> ldydewinter@... writes:

>

> My doctor gave me MTX in pill form, which I took on Thursday. I

have

> to say, I feel incredible! The only pain I feel now is a slight

ache

> in my arm. But everyone here seems to have terrible side effects

from

> MTX. When did these start? I took MTX about eleven years ago when

it

> was still only used for leukemia (which I had). I don't remember

having

> any specific side effects from just MTX, but I had side effects

from

> alot of the other drugs at the time. I'm really hoping I bypassed

any

> nasty side effects and can get on with my life. I haven't felt this

> good in a long time.

> in TN

>

> You are lucky. I started on 6 Mtx on a Monday. I started feeling

nauseated

> and more tired than usual -- like I was getting the flu. I expected

it to last

> a day, but on the third day I was still feeling sick. After a

couple of

> week, the RA doc reduced it to 4 pills a week and added Arava.

>

> I still feel sick each week and now I've started to get terrible

fatigue on

> Sunday -- the day before I take them. Maybe Mtx and you just mesh.

>

> dd

>

> Recent Activity

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[Guest guest]

,

I agree. Members also should keep in mind that most people who join

and stay with our group probably have more problems with their RA than

average.

Not an MD

On Sun, Oct 5, 2008 at 11:32 PM, <McNacks@...> wrote:

> I just have to post that it drives me crazy that so many from this group

> give the impression that you are going to have side effects if you take MTX

> and it's just not true for the majority of people out there on it. I can't

> imagine how scared someone recently diagnosed with RA must feel. I have been

> on it for 9 years now and my only side effect is slight thinning of my hair

> on top, slight. It gave me my life back. MTX is the standard of care for RA,

> don't be afraid to give it a try. I know quite a few people on it presently

> and I have had a discussion with my RA doc about how many of his patients on

> it do well. in PA

[Guest guest]

Jacky,

I take 3 pills a week, I have been up to 4 in the past.

My RA came on overnight, actually I know the date, it was truly one day I was

fine and the next I was on the sofa unable to do anything, in pain with fevers.

After trying for a diagnosis with the primary for 2 weeks, he finally suggested

a rheumy, I waited 6 weeks to get in and then the magic started. I thought it

was such a relief to have a name placed on my condition, it might not be a great

name but at least I finally knew what I was fighting. I read everything I

could, got an understanding of the disease and picked my medicine. My doctor at

that time presented everything available out there, the patient picked. Now

originally I didn't like that, I felt that he knew what was best but then I also

thought, well, at least he's not owned by the drug companies and going for the

one that will make him the most money. So I chose MTX since it has been around

so long, the biologics scared me at that time, that was 9 years ago, but I have

since tried Remicade, it just didn't work fo

r me so well (I do know 2 men on it that it is working wonderful for, they both

are longshoremen and work long hours with no problems) and I would consider

another biologic if the MTX stopped working.

Good Luck, in PA

-------------- Original message --------------

From: " pawsitivepuppy " <pawsitivepuppy@...>

Hi and all, thanks for posting this,. i was getting pretty

scared reading some of the posts re mtx. I'm so glad to read that

you are doing well with it.

I do not have a diagnosis yet. I am going to the rheumy for first

time this Tuesday. My feet and hands hurt and are stiff, and my

ankles and knees are swollen. I cant get up and down steps anymore,

and i can barely walk. I struggle to get up out of chairs because

of my knees. I cant get my groceries or walk my dog. And i am only

51. This has started near the beginning of 2008 and continually

getting worse, especially in the last couple months with my knees

swelling.

So i hope the rheumy can prescribe some med for me that will help.

Do you take MTX pills or injections?

Jacky in Canada

>

> I just have to post that it drives me crazy that so many from this

group give the impression that you are going to have side effects if

you take MTX and it's just not true for the majority of people out

there on it. I can't imagine how scared someone recently diagnosed

with RA must feel. I have been on it for 9 years now and my only

side effect is slight thinning of my hair on top, slight. It gave me

my life back. MTX is the standard of care for RA, don't be afraid to

give it a try. I know quite a few people on it presently and I have

had a discussion with my RA doc about how many of his patients on it

do well. in PA

>

> -------------- Original message --------------

> From: dgd301@...

>

>

> In a message dated 10/5/2008 5:58:46 P.M. Central Daylight Time,

> ldydewinter@... writes:

>

> My doctor gave me MTX in pill form, which I took on Thursday. I

have

> to say, I feel incredible! The only pain I feel now is a slight

ache

> in my arm. But everyone here seems to have terrible side effects

from

> MTX. When did these start? I took MTX about eleven years ago when

it

> was still only used for leukemia (which I had). I don't remember

having

> any specific side effects from just MTX, but I had side effects

from

> alot of the other drugs at the time. I'm really hoping I bypassed

any

> nasty side effects and can get on with my life. I haven't felt this

> good in a long time.

> in TN

>

> You are lucky. I started on 6 Mtx on a Monday. I started feeling

nauseated

> and more tired than usual -- like I was getting the flu. I expected

it to last

> a day, but on the third day I was still feeling sick. After a

couple of

> week, the RA doc reduced it to 4 pills a week and added Arava.

>

> I still feel sick each week and now I've started to get terrible

fatigue on

> Sunday -- the day before I take them. Maybe Mtx and you just mesh.

>

> dd

>

> Recent Activity

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[Guest guest]

Hi - I'm sorry to hear that it " drives you crazy " that " so many

of us " give the impression of negative side effects with MTX. I read

all the posts and I didn't get that impression at all. I think it is

important to not only report the good, but the bad and ugly of these

meds so that people can make an informed decision when trying a new

one. Its one thing to read the literature provided by the pharmacy and

another thing to hear various experiences from actual patients. For

me, MTX only causes extreme fatigue the day of and sleepiness for a

day or two afterward. Again, for me, I am still out of control with my

RA/FMS symptoms and having no insurance makes it difficult to explore

some of the more effective meds that are available.

I'm glad to hear that you are having good luck with the MTX with

minimal side effects. You are one of the success stories.

Doreen

I just have to post that it drives me crazy that so many from this

group give the impression that you are going to have side effects if

you take MTX and it's just not true for the majority of people out

there on it. I can't imagine how scared someone recently diagnosed

with RA must feel. I have been on it for 9 years now and my only side

effect is slight thinning of my hair on top, slight. It gave me my

life back. MTX is the standard of care for RA, don't be afraid to

give it a try. I know quite a few people on it presently and I have

had a discussion with my RA doc about how many of his patients on it

do well. in PA

[Guest guest]

Doreen,

I posted that because the majority of posts here are against MTX for one reason

or another. I'm just saying that if you are new to this disease, it must scare

the hell out of you to be prescribed MTX after reading a few of the posts. I

also think it's important to report the good and the bad, it's just that the bad

seems to run 20 to 1. I just don't want to scare someone recently diagnosed.

in PA

-------------- Original message --------------

From: " Mimi " <mimi212@...>

Hi - I'm sorry to hear that it " drives you crazy " that " so many

of us " give the impression of negative side effects with MTX. I read

all the posts and I didn't get that impression at all. I think it is

important to not only report the good, but the bad and ugly of these

meds so that people can make an informed decision when trying a new

one. Its one thing to read the literature provided by the pharmacy and

another thing to hear various experiences from actual patients. For

me, MTX only causes extreme fatigue the day of and sleepiness for a

day or two afterward. Again, for me, I am still out of control with my

RA/FMS symptoms and having no insurance makes it difficult to explore

some of the more effective meds that are available.

I'm glad to hear that you are having good luck with the MTX with

minimal side effects. You are one of the success stories.

Doreen

I just have to post that it drives me crazy that so many from this

group give the impression that you are going to have side effects if

you take MTX and it's just not true for the majority of people out

there on it. I can't imagine how scared someone recently diagnosed

with RA must feel. I have been on it for 9 years now and my only side

effect is slight thinning of my hair on top, slight. It gave me my

life back. MTX is the standard of care for RA, don't be afraid to

give it a try. I know quite a few people on it presently and I have

had a discussion with my RA doc about how many of his patients on it

do well. in PA