RESEARCH - Are biologics more effective than classical DMARDs?

[Guest guest]

Arthritis Research & Therapy 2008, 10:118doi:10.1186/ar2491

Commentary

Are biologics more effective than classical disease-modifying

antirheumatic drugs?

T Nurmohamed1,2 and Ben AC Dijkmans1,2

1Department of Rheumatology, VU University Medical Centre, De

Boelelaan 1117, 1081 HV Amsterdam, The Netherlands

2Department of Rheumatology, Jan van Breemen Institute, Dr Jan van

Breemenstraat 2, 1056 AB Amsterdam, The Netherlands

Published: 19 September 2008

Abstract

Major achievements have been reached in the treatment of rheumatoid

arthritis during past decades due to the recognition of methotrexate

as an anchor drug for treatment of rheumatoid arthritis, due to the

notion of a treatment window of opportunity in patients with

recent-onset rheumatoid arthritis necessitating early aggressive

therapy, due to the development of biologics and due to remission as a

treatment target. Most biologics have a much faster onset of action

than synthetic disease-modifying anti-rheumatic drugs, but presently

there is no convincing evidence that biologic drugs have a superior

clinical efficacy in comparison with the synthetic drugs. Biologics

are, however, accompanied by less radiological deterioration.

http://arthritis-research.com/content/10/5/118/abstract

Not an MD

[Guest guest]

,

Interesting Abstract. Is the full article available?

Bob

>

> Arthritis Research & Therapy 2008, 10:118doi:10.1186/ar2491

> Commentary

>

>

> Are biologics more effective than classical disease-modifying

> antirheumatic drugs?

>

>

> T Nurmohamed1,2 and Ben AC Dijkmans1,2

> 1Department of Rheumatology, VU University Medical Centre, De

> Boelelaan 1117, 1081 HV Amsterdam, The Netherlands

> 2Department of Rheumatology, Jan van Breemen Institute, Dr Jan van

> Breemenstraat 2, 1056 AB Amsterdam, The Netherlands

>

>

> Published: 19 September 2008

>

> Abstract

>

> Major achievements have been reached in the treatment of rheumatoid

> arthritis during past decades due to the recognition of methotrexate

> as an anchor drug for treatment of rheumatoid arthritis, due to the

> notion of a treatment window of opportunity in patients with

> recent-onset rheumatoid arthritis necessitating early aggressive

> therapy, due to the development of biologics and due to remission as a

> treatment target. Most biologics have a much faster onset of action

> than synthetic disease-modifying anti-rheumatic drugs, but presently

> there is no convincing evidence that biologic drugs have a superior

> clinical efficacy in comparison with the synthetic drugs. Biologics

> are, however, accompanied by less radiological deterioration.

>

>

> http://arthritis-research.com/content/10/5/118/abstract

>

>

>

> Not an MD

>

[Guest guest]

Bob,

Sorry. The full article is available only to subscribers.

If the full article is free, I do list the link and write words to the

effect: " Read the full article here: "

Not an MD

On Sun, Oct 12, 2008 at 5:44 AM, fullwave2 <w8nyy.1@...> wrote:

> ,

> Interesting Abstract. Is the full article available?

> Bob

[Guest guest]

GINA AND GROUP;

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gentle hugs

Clora

[Guest guest]

Glad you have your PC back, Clora.

So you're saying that you have osteoarthritis, not osteoporosis?

Not an MD

On Mon, Oct 13, 2008 at 3:14 PM, CLORA <clora4jesus@...> wrote:

> GINA AND GROUP;

>

> WOO HOO I got my pc back working great... OMG I am so happy.. Since

> the pc guy is a friend of the family he only charge me 25 dollars for

> parts... wow... I got 100 post so I better get busy and see what

> everyone has been doing..

>

> I almost forgot... I went to the rheumy today... SHe gave me Volteran

> for the osteo pain any one every hear of it.. Or is taking it.. How is

> it working... I have to see my cardiologist for the walker.. I will see

> him in 2 months...

>

> gentle hugs

> Clora