Re: RESEARCH - IL-6 receptor inhibition with tocilizumab reduces disease activity in RA with inadequate response to DMARDs

[Guest guest]

Wow, - this is the study that I've been taking part in. I think I

am getting the placebo, though, because after 3 IV Infusions, I am not

any better and getting worse all the time........Doreen

>

> Arthritis Rheum. 2008 Sep 29;58(10):2968-2980.

>

>

> Interleukin-6 receptor inhibition with tocilizumab reduces disease

> activity in rheumatoid arthritis with inadequate response to

> disease-modifying antirheumatic drugs: The tocilizumab in

> combination with traditional disease-modifying antirheumatic drug

> therapy study.

>

> CONCLUSION: Tocilizumab combined with any of the DMARDs evaluated

> was safe and effective in reducing articular and systemic symptoms

> in patients with an inadequate response to these agents.

>

> PMID: 18821691

>

> http://www.ncbi.nlm.nih.gov/pubmed/18821691

>

>

>

> Not an MD

>

[Guest guest]

Sorry, Doreen.

I hope you'll be able to try the real thing soon so you can get some relief.

Not an MD

On Thu, Oct 9, 2008 at 9:07 AM, Mimi <mimi212@...> wrote:

> Wow, - this is the study that I've been taking part in. I think I

> am getting the placebo, though, because after 3 IV Infusions, I am not

> any better and getting worse all the time........Doreen

[Guest guest]

Doreen and group;

How much longer is this study Doreen??? I pray for you to feel

better.. Will this prayer interfere with the study??? I think that

they should end this study for you so you can get treated... j

I know your being strong for this study but you deserve some relief

from so much pain.. It is only my opinion.. I love everyone here and

pray that you all have pain free days..

gentle hugs

Clora

> Wow, - this is the study that I've been taking part in. I

think I

> am getting the placebo, though, because after 3 IV Infusions, I am

not

> any better and getting worse all the time........Doreen

>

>

> >

> > Arthritis Rheum. 2008 Sep 29;58(10):2968-2980.

> >

> >

> > Interleukin-6 receptor inhibition with tocilizumab reduces disease

> > activity in rheumatoid arthritis with inadequate response to

> > disease-modifying antirheumatic drugs: The tocilizumab in

> > combination with traditional disease-modifying antirheumatic drug

> > therapy study.

> >

> > CONCLUSION: Tocilizumab combined with any of the DMARDs evaluated

> > was safe and effective in reducing articular and systemic

symptoms

> > in patients with an inadequate response to these agents.

> >

> > PMID: 18821691

> >

> > http://www.ncbi.nlm.nih.gov/pubmed/18821691

> >

> >

> >

> > Not an MD

> >

>

[Guest guest]

Thank you and Clora. I have made the decision to stop

participating in the clinical study. To have continued for one more

month could have meant another placebo infusion and then waiting

another month before the escape arm could be activated. Then again, if

I was getting the real drug, it could have meant another month of

ineffective treatment with no escape arm. I need to place a call to my

rheumy this morning. They were not very efficient with callbacks this

past week and if this keeps up, I will be finding a new one.....Doreen

[Guest guest]

Sorry, Doreen. I hope your rheumatologist (should you keep him) have

some good ideas about what to do next.

Not an MD

On Mon, Oct 13, 2008 at 5:03 AM, Mimi <mimi212@...> wrote:

> Thank you and Clora. I have made the decision to stop

> participating in the clinical study. To have continued for one more

> month could have meant another placebo infusion and then waiting

> another month before the escape arm could be activated. Then again, if

> I was getting the real drug, it could have meant another month of

> ineffective treatment with no escape arm. I need to place a call to my

> rheumy this morning. They were not very efficient with callbacks this

> past week and if this keeps up, I will be finding a new one.....Doreen