Re: REVIEW - Immunization of patients with RA with anti-TNF therapy and MTX

[Guest guest]

and group;

can you tell me from this report if it says it's ok to get flue

shot if you have RA. Or it is undetermined. Sorry I don't understand

the results. I don't need a lengthy explainationa. Unless you

really want too.

I am just wondering if they think its ok for flue shots its not ok or

they just don't know for those with RA. NO offence intended. If

anyone else understands it they are doctors or have a docorate

degree. lol haaaaaaaaaaaaaaaaaaaaaaaaa.

That was funny. I am still laughing heehehehaahahaha. I don't

understand a word of it and I went to college for 2 years for RN. I

see flue and shot here and there lol. Of course that was many many

years ago.

Love you so much

gentle hugs

Clora May

:**************************************************************

>

> Curr Opin Rheumatol. 2008 May;20(3):295-9.

>

>

> Immunization of patients with rheumatoid arthritis with antitumor

> necrosis factor alpha therapy and methotrexate.

>

>

> Brezinschek HP, Hofstaetter T, Leeb BF, Haindl P, Graninger WB.

> Division of Rheumatology, Department of Internal Medicine, Medical

> University Graz, Graz, Austria.

>

>

> PURPOSE OF REVIEW: The aim of this study is to highlight the recent

> findings on the use of methotrexate and/or TNFalpha-blockers in

adult

> patients with rheumatoid arthritis and their effects on the immune

> response to various vaccines. RECENT FINDINGS: Regarding influenza

> vaccination, methotrexate monotherapy is not associated with a

> decreased response, whereas the use of etanercept and infliximab in

> combination with methotrexate may cause lower titers and lower

> response rates. Concerning pneumococcal vaccination, methotrexate

> seems to impair responsiveness. The concomitant use of adalimumab

and

> methotrexate is also associated with decreased response, whereas the

> concomitant use of etanercept or infliximab seems not to have an

> effect on response rates. As immunological pathways seem to play a

> major role, T-cell-dependent pneumococcal vaccines are designed to

> achieve higher response rates and protective titers. SUMMARY:

Patients

> with rheumatic disorders are more likely to develop preventable

> infectious diseases, which underlines the importance of adequate

> immunoprotective titers. Several studies have shown that the

> combination of methotrexate and certain TNFalpha-blockers are

> affecting the responsiveness to vaccines. Further findings indicate

> that the response also depends on what type of vaccine is used.

>

>

> PMID: 18388521

>

> http://www.ncbi.nlm.nih.gov/pubmed/18388521

>

>

>

> Not an MD

>

[Guest guest]

Clora,

This review explored whether RA patients receiving a TNF blocker plus

MTX would benefit from receiving various vaccines.

Since those DMARDs suppress the immune system, when people using them

receive a vaccine, their immune systems may not respond to the vaccine

strongly enough to provide adequate protection should they become

infected with the real thing.

Generally, it's safe for such patients to receive the killed vaccines,

but whether the vaccine will work is the question.

Not an MD

On Sun, Nov 2, 2008 at 11:52 AM, CLORA <clora4jesus@...> wrote:

> and group;

>

> can you tell me from this report if it says it's ok to get flue

> shot if you have RA. Or it is undetermined. Sorry I don't understand

> the results. I don't need a lengthy explainationa. Unless you

> really want too.

>

> I am just wondering if they think its ok for flue shots its not ok or

> they just don't know for those with RA. NO offence intended. If

> anyone else understands it they are doctors or have a docorate

> degree. lol haaaaaaaaaaaaaaaaaaaaaaaaa.

>

> That was funny. I am still laughing heehehehaahahaha. I don't

> understand a word of it and I went to college for 2 years for RN. I

> see flue and shot here and there lol. Of course that was many many

> years ago.

>

> Love you so much

> gentle hugs

> Clora May

[Guest guest]

 

Ok please. Do I have a tnf blocker.  I take for RA ,  humira injections, 

plagunil.  thank you

 

gentle hugs

Clora may

 

> and group;

>

> can you tell me from this report if it says it's ok to get flue

> shot if you have RA. Or it is undetermined. Sorry I don't understand

> the results. I don't need a lengthy explainationa. Unless you

> really want too.

>

> I am just wondering if they think its ok for flue shots its not ok or

> they just don't know for those with RA. NO offence intended. If

> anyone else understands it they are doctors or have a docorate

> degree. lol haaaaaaaaaaaaaaaaaa aaaaaaa.

>

> That was funny. I am still laughing heehehehaahahaha. I don't

> understand a word of it and I went to college for 2 years for RN. I

> see flue and shot here and there lol. Of course that was many many

> years ago.

>

> Love you so much

> gentle hugs

> Clora May

[Guest guest]

Yes, Clora, Humira is a TNF blocker.

Not an MD

On Sun, Nov 2, 2008 at 12:28 PM, Clora <clora4jesus@...> wrote:

>

>

> Ok please. Do I have a tnf blocker. I take for RA , humira injections,

> plagunil. thank you

>

> gentle hugs

> Clora may

[Guest guest]

QUOTE: " Generally, it's safe for such patients to receive the killed vaccines,

but whether the vaccine will work is the question. "

This is EXACTLY what both my rheumy and my PCP stated to me. Yes, it is safe but

you still may get it.... At best, if we get it, it SHOULD be less severe. But

hey.... With our compromised immune systems, who knows, right?????

*~ Kami ~*

Re: [ ] Re: REVIEW - Immunization of patients with RA with

anti-TNF therapy and MTX

Clora,

This review explored whether RA patients receiving a TNF blocker plus

MTX would benefit from receiving various vaccines.

Since those DMARDs suppress the immune system, when people using them

receive a vaccine, their immune systems may not respond to the vaccine

strongly enough to provide adequate protection should they become

infected with the real thing.

Generally, it's safe for such patients to receive the killed vaccines,

but whether the vaccine will work is the question.

Not an MD

On Sun, Nov 2, 2008 at 11:52 AM, CLORA <clora4jesus@...> wrote:

> and group;

>

> can you tell me from this report if it says it's ok to get flue

> shot if you have RA. Or it is undetermined. Sorry I don't understand

> the results. I don't need a lengthy explainationa. Unless you

> really want too.

>

> I am just wondering if they think its ok for flue shots its not ok or

> they just don't know for those with RA. NO offence intended. If

> anyone else understands it they are doctors or have a docorate

> degree. lol haaaaaaaaaaaaaaaaaaaaaaaaa.

>

> That was funny. I am still laughing heehehehaahahaha. I don't

> understand a word of it and I went to college for 2 years for RN. I

> see flue and shot here and there lol. Of course that was many many

> years ago.

>

> Love you so much

> gentle hugs

> Clora May

[Guest guest]

Kami and group;

 

That's so true.  Last June I was in the hospital for pneumonia I said but,  I

had the pneumonia shot. He said.  " They don't always work. "    I thought haaaaa

why take it.  It may have been worse if I hadn't taken it I guess. 

 

I wasn't on any TNF blockers.  Unless plaqunil is one.  I am still glad I took

it.  Especially the flue shot every time if I get the flue it would not last as

long or be as bad.  Now I don't know cause I am taking Humira Injections. 

said that was a TNF Blocker. 

 

Talking about our meds.  I haven't taken my humira injection yet.  I feel like I

have a sinus cold.  I am waiting to see if it clears up.  I got a flue shot

Thursday.  I think its just the after affect from the flue shot.  My daughter

has a sinus infection and she lives with us.  So I am waiting. 

 

 Well Kami we will see hon I pray neither one of us gets the flue.  I pray all

of us stay healthy this winter.  Take care and God bless.

 

gentle hugs

Clora

 

> and group;

>

> can you tell me from this report if it says it's ok to get flue

> shot if you have RA. Or it is undetermined. Sorry I don't understand

> the results. I don't need a lengthy explainationa. Unless you

> really want too.

>

> I am just wondering if they think its ok for flue shots its not ok or

> they just don't know for those with RA. NO offence intended. If

> anyone else understands it they are doctors or have a docorate

> degree. lol haaaaaaaaaaaaaaaaaa aaaaaaa.

>

> That was funny. I am still laughing heehehehaahahaha. I don't

> understand a word of it and I went to college for 2 years for RN. I

> see flue and shot here and there lol. Of course that was many many

> years ago.

>

> Love you so much

> gentle hugs

> Clora May

[Guest guest]

Thanks for your excellent research. I'm going to call the rheumatologist's

office

tomorrow and ask the nurse what they're generally doing with patients on MTX and

Humira. Maybe I misunderstood the doctor.

I do remember from last year (when I was on MTX but not Humira) that he said it

was

good to take the flu shot in November. He said it will stretch-out the effect

through

more of the Winter months, versus taking it a month or 2 earlier and having the

immunity end earlier.

Since I've had RA, everytime that I catch a cold (or sinus infection) it

generally goes to my

lungs and results in 6-8 weeks of bronchitis. My internist puts me on an

antibiotic at

the beginning of every infection but it doesn't stop the long, drawn-out

bronchitis and

coughing.

Does anyone else have that problem? Do you recover from colds slower than you

did

before RA?

Stay well,

Joy

> > and group;

> >

> > can you tell me from this report if it says it's ok to get flue

> > shot if you have RA. Or it is undetermined. Sorry I don't understand

> > the results. I don't need a lengthy explainationa. Unless you

> > really want too.

> >

> > I am just wondering if they think its ok for flue shots its not ok or

> > they just don't know for those with RA. NO offence intended. If

> > anyone else understands it they are doctors or have a docorate

> > degree. lol haaaaaaaaaaaaaaaaaaaaaaaaa.

> >

> > That was funny. I am still laughing heehehehaahahaha. I don't

> > understand a word of it and I went to college for 2 years for RN. I

> > see flue and shot here and there lol. Of course that was many many

> > years ago.

> >

> > Love you so much

> > gentle hugs

> > Clora May

>

[Guest guest]

Group;

 

Now I know why I was seeing double this morning and had a hard time reading your

post.  My husband had the setting on smaller.  I need it on largest to see it

haaaaaaaaaa.   As for the sillyness.  I am silly anyway sometimes.  Love you

all.

 

gentle hugs

Clora