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Re: Fats & Cholester

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Thank you for your very helpful review.

So even the less-quality coconut oil, has been a help to him to keep

the LDL's healthy.

Of course, he should watch if his body can 'normalize' from high

Cholesterol.

Thanks again

-Dan.

> > Hi Dan,

> >

> > > His pattern is 'A'. So would it be right to conclude he has too

much

> > > LDL but it is not (all) bad LDL (pattern b or a/b), which may

be a

> > > relief.

> >

> > Well that is good. I was thinking the more the ApoB is elevated,

the

> > closer it is to A/B or B, but his ApoB seemed only a little

elevated

> > anyway. Of course, A, A/B and B are only three designations for

what

> > is a continuous spectrum, thus one could have better A and A that

is

> > less good.

>

> Oh, I see why it worked out this way. The LDL-to-ApoB ratio would

be

> what would indicate the particle size. So, the reason he had high

> ApoB but pattern A is because his LDL was more elevated than his

ApoB

> was. If his ApoB was more elevated than his LDL, that would mean

> there were more particles (bad), whereas LDL being more elevated

than

> ApoB would mean the particles are larger (good).

>

> Chris

>

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Dan,

> What is your take on the HDL2/HDL3 ratio.

>

> He had 15/46 Ratio, telling the desirable HDL2 is in low quantity. Do

> you agree with that interpretation.

If it is of any importance, I'm not sure what that is. HDL2 is rich in

cholesterol whereas HDL3 is rich in triglyceride, having traded

between the two with LDL and other similar particles via cholesterol

ester transport protein. This is generally considered to be bad,

because it tansfers cholesterol to LDL rather than to the liver; this

was the reasoning behind the recent drug torcetrib (sp?) which was

expected to be beneficial but turned out to be harmful. I wonder how

transporting cholesterol to LDL affects the pattern A/pattern B thing.

More cholesterol in LDL makes the particles larger and less

oxidizable and more pattern A, so I'm not sure they know how good/bad

this whole scenario is. There might be importance to this that I am

missing, but I would not give much weight to it with my current

knowledge.

Chris

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> > What is your take on the HDL2/HDL3 ratio.

> >

> > He had 15/46 Ratio, telling the desirable HDL2 is in low quantity. Do

> > you agree with that interpretation.

I would agree with M. that there is not much evidence to support the

clinical importance

of the HDL2/HDL3 ratio.

K.

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