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Re: high dose Vit c and pregnancy - detox, collagen, and fetus

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Here's one more link to a journal article explaining in detail the

effects of ascorbate on heavy metal poisoning (nickel in this case).

Note the bits about the importance of collagen that would also apply to

a developing fetus. So perhaps some of the effect on the ascorbic acid

to create such healthy babies is that it negates the toxicity of the

heavy metals the mother/fetus are exposed to.

This could have amazing applications to prevention of autism which is

often linked to exposure to metals during development!

http://www.ehponline.org/members/2005/7605/7605.html

And while it addresses nickel specifically, it also mentions chromium,

lead, mercury and others.

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Renate, Tom and others,

I haven't yet looked at the articles you have posted and will have to

hold off responding until I get a chance to. It looks like the

information available on this might be a bit better than I understood

it to be at the beginning of the discussion.

One quick note on the enzymes -- there are only eight known

C-dependent enzymes (that we have, and three fungal ones), not eight

classes of enzymes.

However, while I was driving to the chiropractor today I was thinking

about this and realized there is another way of looking at this.

Vitamin C has a number of non-enzymatic roles in the cell, and one of

them appears to be recycling or stabilizing tetrahydrabiopterin (THB).

THB is a cofactor for many enzymes, so, one could say that those

enzyems are indirectly C-dependent.

On the other hand, I do not know whether this role is specific for

vitamin C. If it is through some indirect mechanism like affecting

the oxidant/antioxidant balance of the cell, then I think it is a

stretch to say they are C-dependent. But if it is a very specific

role, so that one could say THB is directly C-dependent, then it would

be legitimate to list THB-dependent enzymes as indirectly C-dependent.

Chris

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