Re: Growth hormone supplement

[Guest guest]

No, I haven't heard of it, though being that it is derived from soy lecithin, I

would wonder how it differs from, say, phosphatidylcholine.

 

Also, I noticed it didn't name the studies which discovered all of these

wonderful attributes.

Do a search on pubmed and see what you come up with.

 

From: Cray Fish <crayfishfeed@...>

Subject: Growth hormone supplement

Date: Tuesday, August 5, 2008, 3:19 PM

http://www.biosyner gy.com/alphaGPC. htm

I posted a question about if anyone had heard of this but the link

didn't work so I am posting this again. Comments/experience s?

[Guest guest]

Why not just take Arginine? It is an amino acid that encourages natural

growth hormone excretion...

Or better yet, eat sweetbreads...

-Lana

" There is nothing more useful than sun and salt. " - Latin proverb

On Tue, Aug 5, 2008 at 5:19 PM, Cray Fish <crayfishfeed@...> wrote:

> http://www.biosynergy.com/alphaGPC.htm

>

> I posted a question about if anyone had heard of this but the link

> didn't work so I am posting this again. Comments/experiences?

>

>

> ------------------------------------

>

>

[Guest guest]

Hey -

> http://www.biosynergy.com/alphaGPC.htm

>

> I posted a question about if anyone had heard of this but the link

> didn't work so I am posting this again. Comments/experiences?

On a cost basis, that's a terrible deal. It's $1.86 per gram. You

can get it for $0.88 per gram here.

<http://www.bulknutrition.com/?products_id=1527

>

As to its efficacy as a growth hormone release stimulator... I think

the available evidence doesn't so much support the idea that it

stimulates the release of more HGH as that it makes the body more

sensitive to what is already being secreted, as in this study.

>> Author: Ceda GP, Ceresini G, Denti L, Marzani G, Piovani E,

>> Banchini A, et al

>> Date: 3/1992

>> Journal: Horm Metab Res

>> Chair of Gerontology and Geriatrics, University of Parma, Italy.

>> Growth hormone (GH) secretion is decreased during aging in humans

>> and in rodents. This decrease may be due to increased hypothalamic

>> somatostatin release, which is inhibited by cholinergic agonists,

>> or to decreased secretion of GHRH. Alpha-glyceryl-phosphorylcholine

>> (alpha-GFC) is a putative acetylcholine precursor used in the

>> treatment of cognitive disorders in the elderly. In order to learn

>> what effect alpha-GFC had on GH secretion, GH-release hormone

>> (GHRH) was given to young and old human volunteers, with or without

>> the addition of alpha-GFC. GH secretion was greater in the younger

>> subjects than in the old individuals, and both groups had a greater

>> GH response to the GHRH+alpha-GFC than to GHRH alone. The

>> potentiating effect of alpha-GFC on GH secretion was more

>> pronounced in the elderly subjects. These findings confirm the

>> observation that aged individuals respond less well to GHRH than

>> younger subjects, and provides further evidence that increased

>> cholinergic tone enhances GH release.

I believe its potential role in cognition has been studied more, but

for whatever reason, most of the studies seem to be constructed to

determine whether it can either prevent or abate cognitive damage

(sometimes the damage is directly induced in the experiment, sometimes

it's due to stroke or age or Alzheimer's or what have you) rather than

to measure its possible effect as a cognition enhancer in healthy

people. Here's one example.

>> Pharmacol Biochem Behav. 1991 Aug;39(4):835-40.

>> Links

>> Effect of a new cognition enhancer, alpha-

>> glycerylphosphorylcholine, on scopolamine-induced amnesia and brain

>> acetylcholine.

>> CM, Govoni S, Battaini F, Bergamaschi S, Longoni A, Giaroni

>> C, Trabucchi M.

>>

>> Institute of Pharmacological Sciences, University of Milan, Italy.

>>

>> The present study investigates the effect of the administration of

>> alpha-glycerylphosphorylcholine (alpha-GPC) on scopolamine-induced

>> amnesia and on brain acetylcholine (ACh) levels and release in

>> rats. The results indicate that alpha-GPC, when administered

>> orally, reverses the amnesia caused by scopolamine in passive

>> avoidance. The peak effect is observed using 600 mg/kg IG, 5 h

>> before training. The effect of the drug is long lasting (up 30 h)

>> in accordance with its pharmacokinetic characteristics. Since,

>> alpha-GPC administered IG is cleaved within the gut mucosal cells

>> to glycerophosphate and free choline, it is tempting to speculate

>> that this drug acts by increasing the ACh precursor pool. This view

>> is supported also by the observation that alpha-GPC partially

>> counteracts the decrease of brain ACh levels elicited by

>> scopolamine administration. The effect is observed in the

>> hippocampus and cortex, but not in the striatum. Moreover, in ex

>> vivo experiments, alpha-GPC is able to increase the amount of ACh

>> released by rat hippocampus slices following potassium stimulation.

That said, a lot of people swear by it in the nootropic community.

At any rate, what would your goal be in taking it?

-

[Guest guest]

, the reason I would take it is b/c I don't sleep very well and I

have aged drastically in the last three years of very little sleep so

I am concerned about my growth hormone being released etc to repair

what needs repairing.

>

> Hey -

>

> > http://www.biosynergy.com/alphaGPC.htm

> >

> > I posted a question about if anyone had heard of this but the link

> > didn't work so I am posting this again. Comments/experiences?

>

> On a cost basis, that's a terrible deal. It's $1.86 per gram. You

> can get it for $0.88 per gram here.

<http://www.bulknutrition.com/?products_id=1527

> >

>

> As to its efficacy as a growth hormone release stimulator... I think

> the available evidence doesn't so much support the idea that it

> stimulates the release of more HGH as that it makes the body more

> sensitive to what is already being secreted, as in this study.

>

> >> Author: Ceda GP, Ceresini G, Denti L, Marzani G, Piovani E,

> >> Banchini A, et al

> >> Date: 3/1992

> >> Journal: Horm Metab Res

> >> Chair of Gerontology and Geriatrics, University of Parma, Italy.

> >> Growth hormone (GH) secretion is decreased during aging in humans

> >> and in rodents. This decrease may be due to increased hypothalamic

> >> somatostatin release, which is inhibited by cholinergic agonists,

> >> or to decreased secretion of GHRH. Alpha-glyceryl-phosphorylcholine

> >> (alpha-GFC) is a putative acetylcholine precursor used in the

> >> treatment of cognitive disorders in the elderly. In order to learn

> >> what effect alpha-GFC had on GH secretion, GH-release hormone

> >> (GHRH) was given to young and old human volunteers, with or without

> >> the addition of alpha-GFC. GH secretion was greater in the younger

> >> subjects than in the old individuals, and both groups had a greater

> >> GH response to the GHRH+alpha-GFC than to GHRH alone. The

> >> potentiating effect of alpha-GFC on GH secretion was more

> >> pronounced in the elderly subjects. These findings confirm the

> >> observation that aged individuals respond less well to GHRH than

> >> younger subjects, and provides further evidence that increased

> >> cholinergic tone enhances GH release.

>

> I believe its potential role in cognition has been studied more, but

> for whatever reason, most of the studies seem to be constructed to

> determine whether it can either prevent or abate cognitive damage

> (sometimes the damage is directly induced in the experiment, sometimes

> it's due to stroke or age or Alzheimer's or what have you) rather than

> to measure its possible effect as a cognition enhancer in healthy

> people. Here's one example.

>

> >> Pharmacol Biochem Behav. 1991 Aug;39(4):835-40.

> >> Links

> >> Effect of a new cognition enhancer, alpha-

> >> glycerylphosphorylcholine, on scopolamine-induced amnesia and brain

> >> acetylcholine.

> >> CM, Govoni S, Battaini F, Bergamaschi S, Longoni A, Giaroni

> >> C, Trabucchi M.

> >>

> >> Institute of Pharmacological Sciences, University of Milan, Italy.

> >>

> >> The present study investigates the effect of the administration of

> >> alpha-glycerylphosphorylcholine (alpha-GPC) on scopolamine-induced

> >> amnesia and on brain acetylcholine (ACh) levels and release in

> >> rats. The results indicate that alpha-GPC, when administered

> >> orally, reverses the amnesia caused by scopolamine in passive

> >> avoidance. The peak effect is observed using 600 mg/kg IG, 5 h

> >> before training. The effect of the drug is long lasting (up 30 h)

> >> in accordance with its pharmacokinetic characteristics. Since,

> >> alpha-GPC administered IG is cleaved within the gut mucosal cells

> >> to glycerophosphate and free choline, it is tempting to speculate

> >> that this drug acts by increasing the ACh precursor pool. This view

> >> is supported also by the observation that alpha-GPC partially

> >> counteracts the decrease of brain ACh levels elicited by

> >> scopolamine administration. The effect is observed in the

> >> hippocampus and cortex, but not in the striatum. Moreover, in ex

> >> vivo experiments, alpha-GPC is able to increase the amount of ACh

> >> released by rat hippocampus slices following potassium stimulation.

>

> That said, a lot of people swear by it in the nootropic community.

>

> At any rate, what would your goal be in taking it?

>

> -

>

>

[Guest guest]

,

Someone recently told me that GABA was really great for helping them

stop thinking and get to sleep. This person had really bad problems

with a 'racing mind' caused by mercury symptoms and it would take them

a long time to fall asleep. After taking GABA they were able to fall

asleep really easily. Maybe it would help you. Iherb.com sells a bulk

powder for pretty cheap by NOW foods.

-

> >

> > Hey -

> >

> > > http://www.biosynergy.com/alphaGPC.htm

> > >

> > > I posted a question about if anyone had heard of this but the link

> > > didn't work so I am posting this again. Comments/experiences?

> >

> > On a cost basis, that's a terrible deal. It's $1.86 per gram. You

> > can get it for $0.88 per gram here.

> <http://www.bulknutrition.com/?products_id=1527

> > >

> >

> > As to its efficacy as a growth hormone release stimulator... I think

> > the available evidence doesn't so much support the idea that it

> > stimulates the release of more HGH as that it makes the body more

> > sensitive to what is already being secreted, as in this study.

> >

> > >> Author: Ceda GP, Ceresini G, Denti L, Marzani G, Piovani E,

> > >> Banchini A, et al

> > >> Date: 3/1992

> > >> Journal: Horm Metab Res

> > >> Chair of Gerontology and Geriatrics, University of Parma, Italy.

> > >> Growth hormone (GH) secretion is decreased during aging in humans

> > >> and in rodents. This decrease may be due to increased

hypothalamic

> > >> somatostatin release, which is inhibited by cholinergic agonists,

> > >> or to decreased secretion of GHRH.

Alpha-glyceryl-phosphorylcholine

> > >> (alpha-GFC) is a putative acetylcholine precursor used in the

> > >> treatment of cognitive disorders in the elderly. In order to

learn

> > >> what effect alpha-GFC had on GH secretion, GH-release hormone

> > >> (GHRH) was given to young and old human volunteers, with or

without

> > >> the addition of alpha-GFC. GH secretion was greater in the

younger

> > >> subjects than in the old individuals, and both groups had a

greater

> > >> GH response to the GHRH+alpha-GFC than to GHRH alone. The

> > >> potentiating effect of alpha-GFC on GH secretion was more

> > >> pronounced in the elderly subjects. These findings confirm the

> > >> observation that aged individuals respond less well to GHRH than

> > >> younger subjects, and provides further evidence that increased

> > >> cholinergic tone enhances GH release.

> >

> > I believe its potential role in cognition has been studied more, but

> > for whatever reason, most of the studies seem to be constructed to

> > determine whether it can either prevent or abate cognitive damage

> > (sometimes the damage is directly induced in the experiment,

sometimes

> > it's due to stroke or age or Alzheimer's or what have you) rather

than

> > to measure its possible effect as a cognition enhancer in healthy

> > people. Here's one example.

> >

> > >> Pharmacol Biochem Behav. 1991 Aug;39(4):835-40.

> > >> Links

> > >> Effect of a new cognition enhancer, alpha-

> > >> glycerylphosphorylcholine, on scopolamine-induced amnesia and

brain

> > >> acetylcholine.

> > >> CM, Govoni S, Battaini F, Bergamaschi S, Longoni A, Giaroni

> > >> C, Trabucchi M.

> > >>

> > >> Institute of Pharmacological Sciences, University of Milan, Italy.

> > >>

> > >> The present study investigates the effect of the administration

of

> > >> alpha-glycerylphosphorylcholine (alpha-GPC) on

scopolamine-induced

> > >> amnesia and on brain acetylcholine (ACh) levels and release in

> > >> rats. The results indicate that alpha-GPC, when administered

> > >> orally, reverses the amnesia caused by scopolamine in passive

> > >> avoidance. The peak effect is observed using 600 mg/kg IG, 5 h

> > >> before training. The effect of the drug is long lasting (up 30 h)

> > >> in accordance with its pharmacokinetic characteristics. Since,

> > >> alpha-GPC administered IG is cleaved within the gut mucosal cells

> > >> to glycerophosphate and free choline, it is tempting to speculate

> > >> that this drug acts by increasing the ACh precursor pool. This

view

> > >> is supported also by the observation that alpha-GPC partially

> > >> counteracts the decrease of brain ACh levels elicited by

> > >> scopolamine administration. The effect is observed in the

> > >> hippocampus and cortex, but not in the striatum. Moreover, in ex

> > >> vivo experiments, alpha-GPC is able to increase the amount of ACh

> > >> released by rat hippocampus slices following potassium stimulation.

> >

> > That said, a lot of people swear by it in the nootropic community.

> >

> > At any rate, what would your goal be in taking it?

> >

> > -

> >

> >

[Guest guest]

,

I really thought Gaba would work for me too especially since Xanax,

the one thing that helps me sleep supposedly works on the same

biochemical pathways. I was also told that the brand is very important

and I switched to a more expensive brand and I did notice an

improvement for a little and then it stopped working as they all stop

working. The main thing I noticed for me is the degree to which I can

let go and stop thinking during the day is the degree I can do this at

night. So it's a whole reprogramming and re-patterning thing for me

but when I am disciplined enough to remember to breathe throughout the

day and curtail my critical thinking abilities, it pays off

incredibly. So I finally got off the supplement hamster wheel for

that but I was just wondering about stuff that could help offset any

damage I incur from not sleeping hence the growth hormone.

> > >

> > > Hey -

> > >

> > > > http://www.biosynergy.com/alphaGPC.htm

> > > >

> > > > I posted a question about if anyone had heard of this but the link

> > > > didn't work so I am posting this again. Comments/experiences?

> > >

> > > On a cost basis, that's a terrible deal. It's $1.86 per gram.

You

> > > can get it for $0.88 per gram here.

> > <http://www.bulknutrition.com/?products_id=1527

> > > >

> > >

> > > As to its efficacy as a growth hormone release stimulator... I

think

> > > the available evidence doesn't so much support the idea that it

> > > stimulates the release of more HGH as that it makes the body more

> > > sensitive to what is already being secreted, as in this study.

> > >

> > > >> Author: Ceda GP, Ceresini G, Denti L, Marzani G, Piovani E,

> > > >> Banchini A, et al

> > > >> Date: 3/1992

> > > >> Journal: Horm Metab Res

> > > >> Chair of Gerontology and Geriatrics, University of Parma,

Italy.

> > > >> Growth hormone (GH) secretion is decreased during aging in

humans

> > > >> and in rodents. This decrease may be due to increased

> hypothalamic

> > > >> somatostatin release, which is inhibited by cholinergic

agonists,

> > > >> or to decreased secretion of GHRH.

> Alpha-glyceryl-phosphorylcholine

> > > >> (alpha-GFC) is a putative acetylcholine precursor used in the

> > > >> treatment of cognitive disorders in the elderly. In order to

> learn

> > > >> what effect alpha-GFC had on GH secretion, GH-release hormone

> > > >> (GHRH) was given to young and old human volunteers, with or

> without

> > > >> the addition of alpha-GFC. GH secretion was greater in the

> younger

> > > >> subjects than in the old individuals, and both groups had a

> greater

> > > >> GH response to the GHRH+alpha-GFC than to GHRH alone. The

> > > >> potentiating effect of alpha-GFC on GH secretion was more

> > > >> pronounced in the elderly subjects. These findings confirm the

> > > >> observation that aged individuals respond less well to GHRH

than

> > > >> younger subjects, and provides further evidence that increased

> > > >> cholinergic tone enhances GH release.

> > >

> > > I believe its potential role in cognition has been studied more,

but

> > > for whatever reason, most of the studies seem to be constructed to

> > > determine whether it can either prevent or abate cognitive damage

> > > (sometimes the damage is directly induced in the experiment,

> sometimes

> > > it's due to stroke or age or Alzheimer's or what have you) rather

> than

> > > to measure its possible effect as a cognition enhancer in healthy

> > > people. Here's one example.

> > >

> > > >> Pharmacol Biochem Behav. 1991 Aug;39(4):835-40.

> > > >> Links

> > > >> Effect of a new cognition enhancer, alpha-

> > > >> glycerylphosphorylcholine, on scopolamine-induced amnesia and

> brain

> > > >> acetylcholine.

> > > >> CM, Govoni S, Battaini F, Bergamaschi S, Longoni A,

Giaroni

> > > >> C, Trabucchi M.

> > > >>

> > > >> Institute of Pharmacological Sciences, University of Milan,

Italy.

> > > >>

> > > >> The present study investigates the effect of the administration

> of

> > > >> alpha-glycerylphosphorylcholine (alpha-GPC) on

> scopolamine-induced

> > > >> amnesia and on brain acetylcholine (ACh) levels and release in

> > > >> rats. The results indicate that alpha-GPC, when administered

> > > >> orally, reverses the amnesia caused by scopolamine in passive

> > > >> avoidance. The peak effect is observed using 600 mg/kg IG, 5 h

> > > >> before training. The effect of the drug is long lasting (up

30 h)

> > > >> in accordance with its pharmacokinetic characteristics. Since,

> > > >> alpha-GPC administered IG is cleaved within the gut mucosal

cells

> > > >> to glycerophosphate and free choline, it is tempting to

speculate

> > > >> that this drug acts by increasing the ACh precursor pool. This

> view

> > > >> is supported also by the observation that alpha-GPC partially

> > > >> counteracts the decrease of brain ACh levels elicited by

> > > >> scopolamine administration. The effect is observed in the

> > > >> hippocampus and cortex, but not in the striatum. Moreover, in

ex

> > > >> vivo experiments, alpha-GPC is able to increase the amount of

ACh

> > > >> released by rat hippocampus slices following potassium

stimulation.

> > >

> > > That said, a lot of people swear by it in the nootropic community.

> > >

> > > At any rate, what would your goal be in taking it?

> > >

> > > -

> > >

> > >