prostate cancer cure - capsaicin

[Guest guest]

This is from lymestrategies (I wonder what the prostate cancer rate

is in places where food is eaten spicy?):

>

> Shared by Bill Riley of St. sburg, FL, " In April 2006 I was

diagnosed with prostate cancer after a biopsy - Gleason score 6(3+3).

I was strongly urged to have the prostate removed immediately. I

refused & starting doing research. I found a Cedars-Sinai Medical

Center/UCLA School of Medicine study that said that capsaicin (the

stuff that makes pepper hot) fed to rats bred to have human prostate

cancer had caused the tumors to die! I have included a link to a good

recap of the study.

>

> I immediately started taking cayenne pepper capsules daily. I took

the equivalent human dose from the study & made that my goal. I

gradually consumed more each week until I reached what I thought was

the right dose (enough cayenne to equal about 5 habanera peppers per

day).

>

> Last month I decided to see a urologist to see what was involved

in " Watchful Waiting " - he wanted to do another biopsy since it had

been two years - I agreed & the results came back clean - they found

no cancer - not a trace! My doctor was stunned & said that in 18

years he had never seen such a result. We had it double checked &

there were no cancerous cells found.

>

> I am confident it was the cayenne that made the tumor shrink to an

undetectable size or disappear - given the study results.

>

> I plan to keep taking it indefinitely & I recommend it to any male

who has been diagnosed with either BPH or any cancer, as it seems to

be effective against ANY cancer. "

>

>

> I found this explanation of how it works:

>

> Capsaicin (8-methyl-N-vanillyl-6-nonenamide) is the active chemical

compound found in the seeds and fruit of chili peppers of the

Capsicum genus such as cayenne pepper. This pepper provides numerous

health benefits. Capsicum is traditionally used for muscular pain,

headaches, to improve circulation and for its gastrointestinal

protective effects? It is also commonly added to herbal formulations

because it acts as a catalyst for other herbs and aids in their

absorption.

>

>

> Many scientific studies have revealed the exciting potential anti-

cancer abilities of capsaicin. Although the exact mechanism(s) is

unclear, capsaicin has been shown to induce apoptosis in many

different types of cancer cells. Apoptosis is a natural form of cell

death that occurs in old or damaged cells that need to be replaced by

new, healthier cells.

>

> Capsaicin has been shown to protect the stomach from various types

of damage by affecting gastric mucosal blood flow as well as mucosal

and bicarbonate secretions. It also has been shown to cause DNA

fragmentation and subsequent apoptosis in human gastric

adenocarcinoma cells by reducing the expression of a cellular protein

that inhibits apoptosis (Bcl-2). Research shows that the number of

abnormal cells killed increased with greater doses of capsaicin.

According to this study, capsaicin induces apoptosis in abnormal

cells by inhibiting NADH-plasma membrane electron transport system by

acting as a quinine analog. Cells generate most of the energy (ATP)

that they need to survive and reproduce via this electron transport

chain, which occurs in the mitochondria (also known as the

powerhouse) inside cells. If this system is disrupted, the cell

cannot generate enough ATP to sustain itself, and the cell dies. By

disrupting the electron transport chain, capsaicin decreases the

amount of energy that is available to cancer cells, and these cells

cannot continue to proliferate. Cancer cells require more energy than

normal cells, because they are growing and dividing more rapidly than

normal cells. A reduced supply of energy caused by capsaicin can have

a major impact on abnormal cells.

>

> In a recent study conducted at the University of Nottingham,

capsaicin was shown to bind to proteins in the mitochondria of

abnormal cells and trigger apoptosis without being harmful to

surrounding normal cells.

>

> This anti-carcinogenic mechanism is surprisingly similar to how NSP

Paw Paw Cell-Reg works.

>

> Dr. Pramod Srivastava and his colleagues conducted a study in which

they discovered that capsaicin triggered apoptosis in human

pancreatic cancer cells, one of the most difficult types of cancer to

treat. Capsaicin increased the number of apoptotic proteins and

reduced tumor size in cancerous pancreatic cells but did not

negatively affect normal pancreatic cells.

>

> Another study showed that capsaicin inhibited the growth of

leukemic cells

> possibly by causing an increase in the production of reactive

oxygen species inside the abnormal cells, which leads to apoptosis.

Capsaicin did not inhibit the growth of normal cells.

>

> Capsaicin has also shown effectiveness in inhibiting ovarian and

breast cancer cells in vitro by decreasing the activity of NADH

oxidase, an enzyme needed for the production of ATP or cellular

energy.

>

> A recent study has shown that capsaicin induced human prostate

cancer cells to undergo apoptosis by inhibiting NF-Kappa Beta, a

mechanism that leads to the expression of certain genes that are

involved in inflammation and the development of cancer. This same

study demonstrated that capsaicin slowed prostate cancer cells by

regulating androgen receptors on the cells and decreased the

production of PSA produced by the abnormal cells.

>

> Recent studies have also demonstrated that capsaicin inhibited the

ability of some chemical carcinogens to bind to DNA3, suggesting that

capsaicin may have cancer preventative properties.

>

> Capsaicin is generally recognized as safe (GRAS) by the FDA in the

United States when used orally and topically in an appropriate

manner. Capsaicin is found in foods that have a long history of being

used in the human diet without harm. This fact lends support to its

good safety profile.

> Capsaicin and other vanilloid compounds show strong evidence of

having promising potential in the fight against many types of cancer.

>