High rate of extensively drug-resistant tuberculosis in Indian AIDS patients.

[Guest guest]

High rate of extensively drug-resistant tuberculosis in Indian AIDS

patients.

RESEARCH LETTERS

Singh, Sarman; Sankar, Manimuthu Mani; Gopinath, Krishnamoorthy

AIDS. 21(17):2345-2347, November 2007.

Abstract:

Fifty-four full-blown AIDS patients suspected of having HIV-

tuberculosis co-infection were investigated for the prevalence of

extensively drug-resistant (XDR) Mycobacterium tuberculosis. Out of

the 54 patients, M. tuberculosis was isolated from 24 (44.4%).

Twelve (50%) isolates of these had resistance to first-line drugs,

whereas four (33.33%) were also resistant to second-line drugs. All

four patients, in whom XDR M. tuberculosis was isolated, died within

2.6 months of diagnosis.

AIDS. 21(17):2345-2347, November 2007.

[Guest guest]

Dear All,

Re: /message/8012

TB coinfection is really taking a dangerous turn among PLHIVs. I have a recent

primary data of MDR tuberculosis with AIDS patients.

Out of 28 AIDS cases with TB co infection whose sputum was put on culture and

sensitivity, 4 had resistance again the two first line Primary Drugs, Rifampicin

and Isoniazide.

Few of our training participants ( Senior Treatment Supervisors- Revised TB

Control Prog, DOTS) from Jharkhand have also acknowledged the similar trend.

Dr Diwakar Tejaswi

Medical Director

Regional AIDS Training Center and \Network in India (RATNEI)

International Health Organizartion

Patna, India

www.ihousa.org

M- 09835078298

e-mail: <diwakartejaswi@...>