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Re: cf gene

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Anyone can be tested to see if they have one copy of a cf gene which

presumably would mean that they carried some version of gene penetration.

The problem is the

same as with testing for CF itself; as there are 900+ mutations known to

date, most

with some degree of penetration and expression, unless the individual is

tested at

some place like s Hopkins or Toronto where they are, under justifying

circum-

stances, willing to test for all known genotypes, the test may not result in

determi-

nation of actual status as carrier or cfer. Usually 30 to 70 genotypes are

tested for,

starting with DeltaF508. I hope this helps,

n Rojas

ps info from Stanford and UCSF cf centers who use a dna lab at San

Capistrano, California

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Charlotte,

We had our 6 year old son wocf tested.WhenEilish was bornLiam was 3 and they

just gave him a sweat test to make sure he didnt have cf(although he'd

already had ).Then when we were going through theIVF process last year(Which

we've know abandone) they took his blood and tested him for his carrier

statusHe doesnt even carry it. So know we know.The blood test wasnt as bad

asI thought it would be.

cf gene

> does anyone know how you would go about finding if brothers or sisters

without CF carry the Cf gene... that have a sibling with CF?

>

> i know that sounds confusing!

>

> charlotte banks

>

>

>

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Hi Charlotte,

You don't say where you are from. If you are from the UK then simply go to

your GP and ask them to send you for the blood test. Providing that you

are reasonably related to somebody wcf there shouldn't be a problem. If

there is change your GP !!

Barry

Father of Harry 1mwcf and Jack 4 1/2 waiting for sweat test.

>

>Reply-To: cfparentsegroups

>To: " Cystic Fibrosis Parents List " <cfparentsegroups>

>Subject: cf gene

>Date: Mon, 27 Nov 2000 11:43:43 -0600

>

>does anyone know how you would go about finding if brothers or sisters

>without CF carry the Cf gene... that have a sibling with CF?

>

>i know that sounds confusing!

>

>charlotte banks

>

>

>

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Charlotte,

If your son has two identifiable mutations, then they can test for those

mutations. The Genzyme 90+ allele test is considered to be the most

comprehensive, right now, I th ink.... anyway, your CF clinic should be able

to help with this....

Jen

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Hi, Charolette-

After our older daughter was diagnosed at 6 & 1/2 (just a year and a half ago),

we had our four yr. old blood tested and then sweat

tested. She was positive as being a carrier with the blood test so we had the

sweat test shortly after-negative thank goodness! God

luck-Christy, mother of Kassi w/cf and Kylii-carrier

Banks wrote:

> does anyone know how you would go about finding if brothers or sisters without

CF carry the Cf gene... that have a sibling with CF?

>

> i know that sounds confusing!

>

> charlotte banks

>

>

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My sister-in-law lived in Scotland when we found out Eilish had cf. And she

went to the dr and was given some sort of throat gargle thing that she

gargled then spat in back in the container then sent it somewhere (Im not

sure where). Apparently they can do DNA on the saliva and they let her know

that she carried F508 from that and it was so simple and she never went near

the dr to get the result.

cf gene

> >Date: Mon, 27 Nov 2000 11:43:43 -0600

> >

> >does anyone know how you would go about finding if brothers or sisters

> >without CF carry the Cf gene... that have a sibling with CF?

> >

> >i know that sounds confusing!

> >

> >charlotte banks

> >

> >

> >

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