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Failure in Europe, but India continues AIDS vaccine trial

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Failure in Europe, but India continues AIDS vaccine trial

New Delhi, March 14 : India decided to continue the AIDS vaccine

trial to find its impact on its population which is ethnically

different from Europe, where the results proved less encouraging,

parliament was informed Friday.

Minister of State for Health and Family Welfare Panabaka Lakshmi said

that the phase 1 vaccine trial of Adeno-associated virus (AAV) was

initiated at National AIDS Research Institute (NARI) in Pune on Feb

2005.

Thirty volunteers participated in the trial and all the trial

participants were followed up for one year.

After the first phase, the second round of the trial was started

after the results from the Phase 1 trials were received from Belgium

and Germany. The data from Belgium and Germany showed that vaccine

was safe and well tolerated.

However, no significant immune response was reported.

" These results were reviewed by the national scientific and ethics

committees and it was decided that although the results from the two

countries showed that the vaccine is only weekly immunogenic,

different results could be expected from Indian populations due to

ethnic differences, " she said.

Hence the trial in Pune was allowed to continue, she added.

IANS

http://www.newkerala.com/one.php?action=fullnews & id=35170

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