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Re: growth hormone

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Thanks Jeannie. Growth hormone suddenly sounds exciting!

Lonnie

Jeannine and Curtis Sawyer wrote:

Lonnie wrote:

>Has anyone experienced this or given growth

>hormones?

Both of my daughters are growth hormone deficiency. Increasing

the

calories had nothing to do with it, but I do know that it is the

first

thing they try to rule out when a deficiency is suspected.

If the

nutritional support doesn't correct it, and I doubt that it will,

because short stature and growth hormone deficiency aren't all

that

uncommon in mito, then growth hormone is the next step.

My youngest has been on it for 10 years with no side effect - at

least

that we've noted. She stopped growing at age 18 months and

was started

on it at 30 months, when her blood sugar became dangerously low.

She

has done well on it and grown well on it. It's a very tiny

needle and

she tolerated the shots very well even as a toddler. It helps

in many

other ways that can benefit kids with metabolic disease.

It has an

impact on carbohydrate metabolism and the ability to lay down muscle

etc.... They are recently realizing the added benefits of

HGH for kids

with metabolic disease.

My older daughter grew, and stayed on her own curve, although she

is

short. But her low blood sugar worsended dramatically at

puberty and

she eventually was started on Growth hormone when all other

interventions failed to keep her blood sugar up. She failed

all of the

GH challenge tests, and has done remarkably well since starting

it 3

years ago.

If there is anything else that I can help you with don't hesitate

to

contact me.

Jeannine

Brought to you by www.imdn.org

- an on-line support group for those affected by mitochondrial disease.

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One other thing on growth hormone... there is (or was) a study going on at

UCSD in the treatment of mtDNA disorders with Growth Hormone. The reason for

the study was that at some point it was observed that new mtDNA did not

harbor the mtDNA defects of the existing mtDNA and therefore they were going

to try and increase the percentage of good mitochondria to bad mitochondria

by " growing " more mitochondria. Because of the specific method by which

this was theorized to work, a documented mtDNA defect must be present, not

just suspected - it has to actually be identified.

I just went and looked at their website and couldn't find the information

that was previously there. Either the study is closed or I just can't find

it!

Terri

>

>Reply-To: Mitoegroups

>To: Mitoegroups

>Subject: growth hormone

>Date: Thu, 22 Jun 2000 10:19:39 -0500

>

>Lonnie wrote:

>

> >Has anyone experienced this or given growth

> >hormones?

>

>Both of my daughters are growth hormone deficiency. Increasing the

>calories had nothing to do with it, but I do know that it is the first

>thing they try to rule out when a deficiency is suspected. If the

>nutritional support doesn't correct it, and I doubt that it will,

>because short stature and growth hormone deficiency aren't all that

>uncommon in mito, then growth hormone is the next step.

>

>My youngest has been on it for 10 years with no side effect - at least

>that we've noted. She stopped growing at age 18 months and was started

>on it at 30 months, when her blood sugar became dangerously low. She

>has done well on it and grown well on it. It's a very tiny needle and

>she tolerated the shots very well even as a toddler. It helps in many

>other ways that can benefit kids with metabolic disease. It has an

>impact on carbohydrate metabolism and the ability to lay down muscle

>etc.... They are recently realizing the added benefits of HGH for kids

>with metabolic disease.

>

>My older daughter grew, and stayed on her own curve, although she is

>short. But her low blood sugar worsended dramatically at puberty and

>she eventually was started on Growth hormone when all other

>interventions failed to keep her blood sugar up. She failed all of the

>GH challenge tests, and has done remarkably well since starting it 3

>years ago.

>

>If there is anything else that I can help you with don't hesitate to

>contact me.

>

>Jeannine

>

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