Re: Saturated Fats Make You Hungry... or so they say.

[Guest guest]

> A friend of mine just sent me an article saying that supposedly

> eating saturated fats makes you more hungry

The article says it makes rats more hungry, was it your friend extrapolating to

people?

> It also says that saturated fats cause insulin resistance. Both are directly

opposed to my personal experience.

at Hyperlipid shows another way to interpret the " insulin resistance "

found with higher sat fat diets. Check out the posts on " Physiological Insulin

Resistance. " Ridiculously oversimplified, when one has a higher fat diet, the

muscles et al are routinely filled with free fatty acids as opposed to glycogen

or glucose, so it is refusing insulin because there is enough energy, and that

is normal and desireable when fats are the preferred energy substrate.

That study didn't talk about the underlying carbs for the poor rodents being

gavaged. Carbs control the fate of fats as they say. Was this fat fed on top

of a normal diet or instead of? i didn't read the paper either. Sure looked

dense.

Connie

[Guest guest]

Based on the abstract, the conclusion of this study is laughable. First of

all, palmitate is the principal product of enogenous fatty acid production

from carbohydrate. Second, the animals were forcefed. No one in real life

force-feeds olive oil, so if the finding

is extrapolated to anything it should be excessive consumption of food in

general.

Palmitate is cytotoxic when it accumulates in the cell. Ordinarily it does

not accumulate because it is effectively stored or burned for energy. it is

ordinarily specifically toxic to cells with metabolic defects like cancer.

That's why it suppresses metastasis, for example, when supplied in beef

tallow to mice. However, reality-defying conditions like gavage or brain

infusion appear to be an exception, unsurprisingly (since the defect is

simply moved from intracellular mtabolism to the regulation of the supply of

the fatty acid to the cell).

Chris

On Tue, Sep 15, 2009 at 4:14 AM, doublethink03 <doublethink03@...>wrote:

>

>

> A friend of mine just sent me an article saying that supposedly eating

> saturated fats makes you more hungry unlike unsaturated fats that satiate.

> It also says that saturated fats cause insulin resistance. Both are directly

> opposed to my personal experience. Anyhow, the article is in German, but the

> reference it gives is in English:

>

> http://www.jci.org/articles/view/36714

>

> I don't really understand all it says, but I thought I might post it here

> for discussion.

>

> Link to the original article (German):

> http://www.spiegel.de/wissenschaft/mensch/0,1518,648939,00.html

>

> I wonder why I've never even once found an article about the dangers of

> sugar, the " food " that almost killed me...

>

>

>

[Guest guest]

Connie,

thank you for your input! Sorry, something was lost in translation there. My

friend didn't say that, she just sent me the German article, which extrapolates

the findings to humans. It does say that the findings are about rats, but it

strongly implies that the infromation applies to humans as well. It also says

that it has been known for a long time that diets high in fat cause insulin

resistance which causes diabetes.

Is this what you were referring to?

http://high-fat-nutrition.blogspot.com/2008/08/physiological-insulin-resistance.\

html

Johannes

>

> > A friend of mine just sent me an article saying that supposedly

> > eating saturated fats makes you more hungry

>

> The article says it makes rats more hungry, was it your friend extrapolating

to people?

>

> > It also says that saturated fats cause insulin resistance. Both are directly

opposed to my personal experience.

>

> at Hyperlipid shows another way to interpret the " insulin resistance "

found with higher sat fat diets. Check out the posts on " Physiological Insulin

Resistance. " Ridiculously oversimplified, when one has a higher fat diet, the

muscles et al are routinely filled with free fatty acids as opposed to glycogen

or glucose, so it is refusing insulin because there is enough energy, and that

is normal and desireable when fats are the preferred energy substrate.

>

> That study didn't talk about the underlying carbs for the poor rodents being

gavaged. Carbs control the fate of fats as they say. Was this fat fed on top

of a normal diet or instead of? i didn't read the paper either. Sure looked

dense.

>

> Connie

>

[Guest guest]

thank you very much for your explanation. I wonder why studies always seem to be

undertaken under such reality-defying conditions. Is that part of science or why

don't they do it under more realistic conditions?

Johannes

--- In , Masterjohn <chrismasterjohn@...>

wrote:

>

> Based on the abstract, the conclusion of this study is laughable. First of

> all, palmitate is the principal product of enogenous fatty acid production

> from carbohydrate. Second, the animals were forcefed. No one in real life

> force-feeds olive oil, so if the finding

> is extrapolated to anything it should be excessive consumption of food in

> general.

>

> Palmitate is cytotoxic when it accumulates in the cell. Ordinarily it does

> not accumulate because it is effectively stored or burned for energy. it is

> ordinarily specifically toxic to cells with metabolic defects like cancer.

> That's why it suppresses metastasis, for example, when supplied in beef

> tallow to mice. However, reality-defying conditions like gavage or brain

> infusion appear to be an exception, unsurprisingly (since the defect is

> simply moved from intracellular mtabolism to the regulation of the supply of

> the fatty acid to the cell).

>

> Chris

>

>

> On Tue, Sep 15, 2009 at 4:14 AM, doublethink03 <doublethink03@...>wrote:

>

> >

> >

> > A friend of mine just sent me an article saying that supposedly eating

> > saturated fats makes you more hungry unlike unsaturated fats that satiate.

> > It also says that saturated fats cause insulin resistance. Both are directly

> > opposed to my personal experience. Anyhow, the article is in German, but the

> > reference it gives is in English:

> >

> > http://www.jci.org/articles/view/36714

> >

> > I don't really understand all it says, but I thought I might post it here

> > for discussion.

> >

> > Link to the original article (German):

> > http://www.spiegel.de/wissenschaft/mensch/0,1518,648939,00.html

> >

> > I wonder why I've never even once found an article about the dangers of

> > sugar, the " food " that almost killed me...

> >

> >

> >

>

>

>

[Guest guest]

> Is this what you were referring to?

>

http://high-fat-nutrition.blogspot.com/2008/08/physiological-insulin-resistance.\

html

>

> Johannes

Yes, that is one of 's articles on physiological insulin resistance.

Interesting isn't it! I heard that one too about sat fat causing insulin

resistance but now I understand it's just from how they measure and not the same

thing as a diabetic's high HbA1c or anything.

Connie

[Guest guest]

Connie,

it's great to have such information available. Articles like the one I posted

are really confusing for laymen like me, because they seem to prove the

" saturated fat is evil " myth. So it's all the more important that there are

people who can clear things up!

Johannes

[Guest guest]

> So it's all the more important that there are

> people who can clear things up!

> Johannes

Yes thank heavens for M and people like at Hyperlipid.

I couldn't agree more. It is scary to think we might be hurting ourselves by

dietary changes and we don't need misinformation.

Connie