Guest guest Posted May 19, 2011 Report Share Posted May 19, 2011 Hi , As you know, many with MS tolerate 3mg better than 4.5mg because of the symptoms you're experiencing. Many do tolerate 4.5mg but if I was you, I'd skip LDN tonight and then start tomorrow at 3mg. What I've learnt is really, LDN is nothing more than an instrument to evoke the opioids and receptors, and these opioids/receptors are what is really doing the good things, so with this mind, depending on the person, less can be more. So don't be afraid to go down. If day time dosing suits you better than night time dosing, then stick to that. I am sharing with you an extract from Dr Zagon about the time of dosing and how the night time dosing protocol came about:- LDN needs to be taken in the evening. I told Bihari this because I reasoned that for 4-6 hr the patient would be without endorphins that would work (the naltrexone would interfere with function in making one feel good). So I advised him to take this in the evening and sleep through the possible uncomfortable feeling of endorphin deprivation. This led to a story about circadian rhythm as the reason. Nonsense, the endorphins - and especially OGF (met-enkephalin) does not have a circadian rhythm. And people who took my advice and used it in the morning found out that they did just as well. Another myth was the fact that LDN raises your immunity. Nonsense again. LDN - and OGF - are natural immunosuppressants. And if LDN was stimulating the immune system it would wreck havoc on autoimmune diseases (e.g., Multiple Sclerosis). So it appears you're doing everything right but perhaps for you, 4.5mg is too high. Hope this helps. Jayne Crocker LDNNow logo the one to use www.LDNNow.com <http://www.ipetitions.com/petition/ldnnow/> Important! Please sign our LDN petition to the European Parliament by clicking here tel: +44 (0) 7877 492 669 < Dr Steele MBE, talking about LDN LDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. .. From: lowdosenaltrexone [mailto:lowdosenaltrexone ] On Behalf Of Nicholls Sent: 19 May 2011 10:58 To: lowdosenaltrexone ; LDN_Users ; mscured Subject: [lowdosenaltrexone] Legs Any help greatly appreciated On 4.5mg early morning dose [not night as sleep deprivation] Legs suffer from continual RLS [restless legs syndrome] and Pins-and-Needles Just driving me crazy Thanks in advance Regards//MS/PPMS Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.