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  • 3 years later...

Hi ,

Sorry you have need to be here, but welcome to the board!

<<Wondering just how high his CEA can go before he has to go on

morphine>>

Did you see post 4963 about CEA?

Because of the unreliability and variability (both between patients

and within a single patient over time!) of CEA, it cannot really be

used to predict anything (survival time, etc.). It can only be used

as a trending marker over time in an attempt to assess treatement

response. There are patients with CEA near NORMAL having to be on

morphine, simply because their cancer does not produce CEA.

If your husband has pain, then he should tell his doctor about it.

If the pain is not too severe, they will start him off on " milder "

painkillers than morphine first ( & work their way up as needed).

Best Wishes,

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Hi --

Congratulations on all the research that you have done for your

husband.

Is your husband's colon cancer in his liver only? Have they

considered oxaloplatin through a hepatic artery infusion pump? I am

aware of one patient taking that now. His CEA has gone from 200 to

10, so I guess that he is one of the lucky people who has responded

well to it. He also had 6 liver mets previously treated by open

field radiofrequency ablation. I am also aware of one patient's

mother who had a 9 cm liver met shrink to 5 cm on chemo, at which

point she had RFA on it. It has been two years without recurrence.

Next year Avastin should become available, so any extension of life

is helpful. CEAs can go into the thousands, so I don't think that

the absolute number is as important as the trend.

Best wishes,

Barry

> Hi, I'm new to this group. My husband was 50 years old last

November

> when he was diagnosed with stage IV colon cancer. His colon was

> almost completely blocked.

>

> He had emergency surgery to resection his colon and remove some

lymph

> nodes. During surgery they also checked his liver and found it

> completely invaded with tumors. He went on Camptosar + 5FU & LU

> (Saltz regimen) until July. His CEA went down from 600 to 200 and

> his biggest liver tumor shrank from 8 cm to 5 cm. Then his CEA

count

> started going back up in July now it is up to 800 and his Dr is

> putting him on Xeloda(5 FU in pill form) & Oxaliplatin.

>

> On the positive side he still has his sense of humor and is in

good

> spirits. (Dr told him CEA up to 800 today - he replied " When it

gets

> to 1000 - Sell! " ) It helps me tremendously. I also try to focus

on

> enjoying our time together rather than dwelling on his future

death

> keeps me from getting depressed.

>

> Have spent hundreds of hours online learning about this cancer.

Can

> almost spell all the latest drugs and their brand equivalents.

>

> Happy to help any one any way I can. Wondering just how high his

CEA

> can go before he has to go on morphine.

>

> Nash

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They removed the one that was blocking his colon. As far as we know

it is only in his liver. They don't do the infusion thing because

he's got too many to count plus one big one that shrank from

Grapefruit to Orange sized. What I have read is that they haven't

really shown any advantage to direct infusion over the other kind. I

asked the Dr after we found the shrinkage if they could at least take

out the big one but they won't because they can't cure him.

See the pic I posted - is not his liver but is the shape his is in.

They just switched to a new regimen. We applied for Avastin &

Erbitux but were denied.

I'm thankful for every day we get but not very hopeful.

> > Hi, I'm new to this group. My husband was 50 years old last

> November

> > when he was diagnosed with stage IV colon cancer. His colon was

> > almost completely blocked.

> >

> > He had emergency surgery to resection his colon and remove some

> lymph

> > nodes. During surgery they also checked his liver and found it

> > completely invaded with tumors. He went on Camptosar + 5FU & LU

> > (Saltz regimen) until July. His CEA went down from 600 to 200

and

> > his biggest liver tumor shrank from 8 cm to 5 cm. Then his CEA

> count

> > started going back up in July now it is up to 800 and his Dr is

> > putting him on Xeloda(5 FU in pill form) & Oxaliplatin.

> >

> > On the positive side he still has his sense of humor and is in

> good

> > spirits. (Dr told him CEA up to 800 today - he replied " When it

> gets

> > to 1000 - Sell! " ) It helps me tremendously. I also try to

focus

> on

> > enjoying our time together rather than dwelling on his future

> death

> > keeps me from getting depressed.

> >

> > Have spent hundreds of hours online learning about this cancer.

> Can

> > almost spell all the latest drugs and their brand equivalents.

> >

> > Happy to help any one any way I can. Wondering just how high his

> CEA

> > can go before he has to go on morphine.

> >

> > Nash

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