Venous congestion and autoimmune disease

[Guest guest]

This is an interesting hypothesis. I have posted it all as some of you might

not be on Facebook.Janet Venous congestion and " autoimmune " disease--Graves

Diseaseby CCSVI in Multiple Sclerosis on Thursday, 24 May 2012 at 17:30 ·Could

autoimmune disease actually be disease of chronic venous congestion? The immune

system goes where blood goes....From the introductory speech by Elliot M.

Frohman, MD, September 2009,The First CCSVI conference in Bologna, Italy In the

three yearss since Dr. Frohman, a neurologist and guest moderator at Dr.

Zamboni's first conference, made that off-hand comment (which I quickly wrote

down, astounded)--New technology, including color doppler scanning--has allowed

researchers to see how slowed blood flow relates to inflammation. This means

that there are new treatments available to help relieve symptoms. Reducing

venous congestion and aiding normalized blood flow reduces inflammation in

" autoimmune " disease. Venous congestion may well be part of the pathogenesis of

these diseases. New research is giving us a better picture of what happens to

the opthalmic vein in Graves Disease. Graves Disease is a disease of the

thyroid gland, which causes it to create too much thyroid hormone and increases

inflammation and swelling in many areas of the body, including the eyes. The

cause of Graves is unknown---the labeling of this disease as autoimmune is based

in theory. Dr. Zamboni believes that autoimmune thyroid disease might be

related to increased collateral flow through the thyroid veins, caused by CCSVI.

The thyroid veins become activated as part of the collateral circle of drainage

when there is chronic obstruction of the internal jugular veins in CCSVI. And

this may impact the thyroid gland and activate the immune reaction and

inflammation. But there is more research needed. As in other situations, like

CCSVI, our understanding of the impact of the veins is woefully incomplete.

CCSVI and Collateral Circulation Although the connection to thyroid disease is

still a hypothesis, we are learning that the opthamalic vein is related to

Graves Disease. Color Doppler imaging of the superior ophthalmic vein in

patients with Graves' orbitopathy before and after treatment of congestive

disease Superior ophthalmic vein flow was significantly reduced in the orbits

affected with congestive Graves' orbitopathy and returned to normal following

treatment. Congestion appears to be a contributing pathogenic factor in the

active inflammatory stage of Graves' orbitopathy. Treatment of GO in the acute

stage is traditionally immunosuppressive (using corticosteroids or

immunosuppressants), but congestive signs sometimes remain despite adequate

treatment and may require orbital decompression. Persistently reduced or

reversed SOV blood flow despite adequate treatment may be an indication for

decompressive surgery in select patients. The current data appear to confirm

this assumption, as most of our patients were in fact treated with orbital

decompression. link Intraocular pressure and superior ophthalmic vein blood

flow velocity in Graves' orbitopathy: relation with the clinical features Ocular

pressure and superior ophthalmic vein blood flow velocity have significant

association with the clinical features of Graves' orbitopathy. The decrease in

SOV–BFV increases the severity of Graves' orbitopathy, and may have a role in

the clinical course of dysthyroid optic neuropathy. link Color Doppler imaging

of the superior ophthalmic vein in different clinical forms of Graves’

orbitopathySOV congestion may be a contributing pathogenic factor in both

congestive and fibrotic myogenic Graves’ orbitopathy. link If relieving venous

congestion helps the vision of those with Graves Disease by preventing optic

neuropathy---does it matter really which comes first--the immune process or

venous congestion? Do the people with Graves Disease need to know? Opening

veins and restoring blood flow helps people by reducing inflammation. It works

in the liver, the legs, the eyes, and the brain. The opthalmic vein

decompression treatment for Graves Disease was not randomized. It was a

surgical procedure given to only those with venous congestion, who still had

slowed flow even after immune modulating or steroid treatment. And these

treating doctors didn't care which came first--the immune reaction of the venous

congestion--they just know that normalizing blood flow heals tissue, and saves

vision.Joan

[Guest guest]

Hi JanetDo you have the link to this?I'd love to post it in Michelangelo'S

Angels so the members can have a talk/think about it.:)Thanks

'What we do in life, echoes through eternity.'

MARCUS AURELIUS (121 - 180 A.D.)

> To: mscured

> From: janetorchard@...

> Date: Fri, 25 May 2012 01:07:15 +0200

> Subject: Venous congestion and " autoimmune " disease

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> This is an interesting hypothesis. I have posted it all as some of you might

not be on Facebook.Janet Venous congestion and " autoimmune " disease--Graves

Diseaseby CCSVI in Multiple Sclerosis on Thursday, 24 May 2012 at 17:30 ·