risks for pancreatitis with byette

November 27, 2008

Risks for Drug Induced Pancreatitis

With all the press lately about the incretin mimetics and pancreatitis our

current intern, Webb, PharmD Candidate, FAMU has taken a look at

the

facts, and compared the chances of pancreatitis among classes of drugs and

how the risk of death from these drugs compare to other things. Find the

numbers

yourself in her feature

Risks for Drug Induced Pancreatitis

Webb, PharmD Candidate, FAMU

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.. Acute pancreatitis affects approximately 80,000 people in the US each year

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.. Chronic pancreatitis is seen more in men than women

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.. Most cases are caused by gallstones and alcohol abuse

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.. Drug induced pancreatitis only account for about 5% of the population

diagnosed with pancreatitis.

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table with 2 columns and 4 rows

Causes of Pancreatitis

Prevalence

Gallstones

45% of reported cases

Alcohol

35% of reported cases

Drug induced

5% of reported cases

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.. Drug induced pancreatitis rarely occurs and the prevalence of such

incidences have been difficult to determine.

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table with 2 columns and 5 rows

Risk of Pancreatitis from

Comments

Incretins

There have been 6 reported cases out of over 1million users but there were

other causatives in each case.

Ace Inhibitors

There have been multiple cases reported but it is impossible to estimate the

prevalence

Thiazide Diuretics

There have been 25 reported cases, but they are thought to be caused by

electrolyte imbalances

Statins

3.9% out of 2576 patients

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Risk of Drug Induced Death

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.. Medication related death is rare

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.. There is a greater risk of death riding in a car than taking a

prescription medication.

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table with 2 columns and 10 rows

Risk of Death from

Population risk per year

Automobile Accidents

1 out of 7,700

Aspirin Therapy

1 out of 10,000

Incretin Therapy

1 out of 350,000

Drowning

1 out of 86,000

Riding a motorcycle

1 out of 91,500

Firearms

1 out of 300,000

Tornados

1 out of 5 million

Lightning

1 out of 6 million

Caffeine

1 out of 100 million

table end

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This article originally posted November 25, 2008 and appeared in

Issue 444

Past five issues:

Issue 444 |

Issue 443 |

Issue 442 |

Issue 441 |

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