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Re: Medication help please (Lyrica)

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Lois Churchill wrote:

> Re: Lyrica

>

> I had been on lyrica (75mg) three times a day for probably three

> years. When my feet became much worse, the Dr, suggested 4 (100mg) a

> day which I faithfully took. In about a week or less I became so

> nauseated and sick all night. I was saying and doing crazy things

> like putting towels all over the bathroom and calling them hangers and

> that I needed more etc. My husband asked our daughter that works at

> the hospital to come to our house.

ALL,

Lyrica seems to have an accumulative effect as you might not have side effects

but after two months I was the same way and last week, I was placed in ICU in an

" altered state " against my will.

So even vitamin deficiencies can make problems.

This is from FDA site and my Doctor would not prescribe that much as she stated

research says more than 300 mg has not shown to do any better.

discontinuing Lyrica, taper gradually over a minimum of 1 week.

Neuropathic pain associated with diabetic peripheral neuropathy

The maximum recommended dose of Lyrica is 100 mg three times a day (300 mg/day)

in patients with creatinine clearance of at least 60 mL/min. Begin dosing at 50

mg three times a day (150 mg/day). The dose may be increased to 300 mg/day

within 1 week based on efficacy and tolerability. Because Lyrica is eliminated

primarily by renal excretion, adjust the dose in patients with reduced renal

function [see Dosage and Administration (2.5)].

Although Lyrica was also studied at 600 mg/day, there is no evidence that this

dose confers additional significant benefit and this dose was less well

tolerated. In view of the dose-dependent adverse reactions, treatment with doses

above 300 mg/day is not recommended [see Adverse Reactions (6.1)].

Bennie

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