over/under methylation TMG GABA Andy??

[Guest guest]

In a message dated 8/23/02 10:57:07 AM Eastern Daylight Time, writes:

> DMG/TMG results are also dependent on under/over methylwhatever. I

> can't remember either LOL. But kids who are one or the other, do

> nasty with DMG/TMG. My kids had a major nasty reaction to TMG.

>

Hi,

Does someone know the answer to this?

I'm trying to understand this relationship with TMG/DMG to methylators

(also serotonin). Also, in relation to sulfur (NAC, epson salt baths etc.)

and the use of no-fenol.

As I understand it, impaired sulfation leads to decreased bile acids

which leads to gut problems which leads to food sensitivities which leads to

neurological problems. The over methylators and under methylators have

something to do with histamine levels -- but I don't remember.

And while I'm asking questions, can anyone explain why you can't give

GABA with Zoloft?

Many thanks,

[Guest guest]

> Does someone know the answer to this?

There isn't a straightforward one.

> I'm trying to understand this relationship with TMG/DMG to

methylators

> (also serotonin). Also, in relation to sulfur (NAC, epson salt baths

etc.)

> and the use of no-fenol.

There is a lot of voodooo psychobabble random misuse and abuse of

words for various purposes in order to make it simple and

straightforward to talk about (e. g. my use of " sulfur foods " when

thiol containing foods and thiol precursor foods would be more

accurate).

The way the Pfeiffer Center people use the words overmethylator and

undermethylator is more related to exactly which part of their methyl

group handling chemistry is slow or fast than to whether it is really

slow (literal undermethylation) or fast (literal overmethylation).

> As I understand it, impaired sulfation leads to decreased

bile acids

> which leads to gut problems which leads to food sensitivities which

leads to

> neurological problems.

Not really.

Sulfation doesn't make much of the bile acid pool.

Impaired sulfation leads to sensitvity to phenols and salycilates as

well as impaired clearance of certain signalling molecules, causing

neurological problems.

>The over methylators and under methylators have

> something to do with histamine levels -- but I don't remember.

Kinda sorta. One way your body gets rid of histamine is to methylate

it. Other things may affect histamine levels. The combination Ca +

Mg + B6 + B12 + folic acid + TMG reduces systemic histamine levels in

most people.

> And while I'm asking questions, can anyone explain why you

can't give

> GABA with Zoloft?

I don't know. Probably because MD's are afraid that once they

prescribe an SSRI that doesn't actually help most people you might

find out that an OTC supplement works and draw the logical conclusion

about the value of going back to the MD to try another drug. . ..

> Many thanks,

>

>

>

> [Non-text portions of this messag

[Guest guest]

I don't even know what methylators (sp) are so I don't know if he

takes any. But I know my nephew (age 3)was on TMG and it really

disrupted his sleep. He no longer wanted to take naps or go to bed at

night. Since my sister stopped giving it to him he went back to

sleeping well.

> In a message dated 8/23/02 10:57:07 AM Eastern Daylight Time, writes:

>

>

> > DMG/TMG results are also dependent on under/over methylwhatever. I

> > can't remember either LOL. But kids who are one or the other, do

> > nasty with DMG/TMG. My kids had a major nasty reaction to TMG.

> >

>

> Hi,

> Does someone know the answer to this?

> I'm trying to understand this relationship with TMG/DMG to

methylators

> (also serotonin). Also, in relation to sulfur (NAC, epson salt baths

etc.)

> and the use of no-fenol.

> As I understand it, impaired sulfation leads to decreased

bile acids

> which leads to gut problems which leads to food sensitivities which

leads to

> neurological problems. The over methylators and under methylators have

> something to do with histamine levels -- but I don't remember.

> And while I'm asking questions, can anyone explain why you

can't give

> GABA with Zoloft?

> Many thanks,

>

>

>

>