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EDITORIAL - Rheumatoid cachexia: a complication of RA moves into the 21st century

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Arthritis Research & Therapy 2009, 11:108doi:10.1186/ar2658

Editorial

Rheumatoid cachexia: a complication of rheumatoid arthritis moves into

the 21st century

Ronenn Roubenoff1,2

1Immunology R & D, Biogen Idec, Inc., Cambridge, MA 02142, USA

2Tufts University and Tufts Medical Center, Boston, MA 02111, USA

Abstract

Rheumatoid cachexia, loss of muscle mass and strength and concomitant

increase in fat mass, is very common in patients with rheumatoid

arthritis (RA). Despite great advances in the treatment of RA, it

appears that rheumatoid cachexia persists even after joint

inflammation improves. Rheumatoid cachexia may be an important risk

factor for cardiovascular disease and excess mortality in RA. In this

issue of Arthritis Research & Therapy, Elkan and colleagues

demonstrate a link between rheumatoid cachexia and metabolic syndrome,

further reinforcing the need for therapy directed beyond inflammation

and at the metabolic consequences of RA.

Read the full editorial here:

http://arthritis-research.com/content/11/2/108

Not an MD

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