Guest guest Posted July 10, 2009 Report Share Posted July 10, 2009 Hi All, Does anyone know how long it takes for methotrexate to take effect? Under a rheumatologist's care,I'm starting at 10 mgs. once a week, then slowly working up to 15mgs. I've so far taken one dose almost a week ago. I am also on prednisone, 5mgs. daily, which I've been on for five weeks (started on a higher dose and worked my way down). I started getting a scary side effect (in the past 5 days) and am wondering if it's from the prednisone, the methotrexate, the combo of both or what? Best to everyone, Ira Quote Link to comment Share on other sites More sharing options...
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