CASE REPORTS - Enbrel-associated pulmonary granulomatous inflammation in patients with RA

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Journal of Rheumatology

November 2008

Etanercept-associated Pulmonary Granulomatous Inflammation in Patients

with Rheumatoid Arthritis

To the Editor:

We describe 4 patients with rheumatoid arthritis (RA) who developed

noninfectious pulmonary granulomatous disease while treated with

etanercept (Table 1). All patients improved with withdrawal of

etanercept and addition of prednisone, without use of antibiotic,

antifungal, or antimycobacterial medications. They were subsequently

treated with adalimumab with no recurrence of pulmonary toxicity.

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http://www.jrheum.com/subscribers/08/11/2279-b.html

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