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RESEARCH - Why do people with RA still die prematurely?

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Ann Rheum Dis. 2008 Dec;67 Suppl 3:iii30-4.

Why do people with rheumatoid arthritis still die prematurely?

SE.

Department of Health Sciences Research, Mayo Foundation, Rochester, MN

55905, USA.

Premature death has been long recognised as a manifestation of

rheumatoid arthritis (RA). Three lines of evidence can explain why

patients with RA die prematurely and why the mortality gap between

patients with RA and the general population appears to widening.

First, patients with RA have a higher risk of several serious comorbid

conditions and they tend to experience worse outcomes after the

occurrence of these illnesses. Second, patients with RA do not appear

to receive optimal primary or secondary preventive care. And third,

the systemic inflammation and immune dysfunction associated with RA

appears to promote and accelerate comorbidity and mortality. This

paper provides a brief summary and interpretation of the data

underlying these findings. Together, these results provide a

compelling argument in favour of a focused research programme aimed

specifically at eliminating premature death in patients with RA.

PMID: 19022810

http://www.ncbi.nlm.nih.gov/pubmed/19022810

Not an MD

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and group;

OMG that last post under here scared the ba hebb jeebes out of me,

but after the 3 reasons was stated, I feel better now. Swosh (wiping

my brough).

Of all the news you put here the one I understand was this one

haaaaaa. That is so funny to me. Love ya.

gentle hugs

Clora

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> Ann Rheum Dis. 2008 Dec;67 Suppl 3:iii30-4.

>

>

> Why do people with rheumatoid arthritis still die prematurely?

>

>

> SE.

> Department of Health Sciences Research, Mayo Foundation, Rochester,

MN

> 55905, USA.

>

>

> Premature death has been long recognised as a manifestation of

> rheumatoid arthritis (RA). Three lines of evidence can explain why

> patients with RA die prematurely and why the mortality gap between

> patients with RA and the general population appears to widening.

> First, patients with RA have a higher risk of several serious

comorbid

> conditions and they tend to experience worse outcomes after the

> occurrence of these illnesses. Second, patients with RA do not

appear

> to receive optimal primary or secondary preventive care. And third,

> the systemic inflammation and immune dysfunction associated with RA

> appears to promote and accelerate comorbidity and mortality. This

> paper provides a brief summary and interpretation of the data

> underlying these findings. Together, these results provide a

> compelling argument in favour of a focused research programme aimed

> specifically at eliminating premature death in patients with RA.

>

>

> PMID: 19022810

>

> http://www.ncbi.nlm.nih.gov/pubmed/19022810

>

>

>

> Not an MD

>

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