Re: Mtx, chloroquine and mobic

June 13, 2009

Hi Dawn - I'm sorry you are having problems with your liver enzymes and happy at

the same time that the MTX seems to be working so well for you. How many ml are

you injecting weekly of the MTX? I inject 0.8ml weekly. Are you taking folic

acid too? I take 1mg of folic acid on every day except the day of the MTX. That

helps with the side effects of the MTX.

There are other things besides MTX that can cause elevated liver enzymes. Most

(if not all) NSAID's carry that risk (Lodine & Mobic included). Do you drink

alcohol at all? I was told by my Rheumy and Pharmacist not to drink any alcohol.

Are you taking any OTC meds like Advil, Tylenol, Alleve? Those can also

contribute to higher liver enzymes and really should not be taken if you are

taking Lodine or Mobic.

I've not taken Chloroquine, but did try Plaquenil (Hydroxychloroquine) which is

in the same group of anti-malarial drugs. I had to discontinue it because it was

messing with my eyesight.

I'm not a doctor, but from experience and what others have posted here, I wonder

if there are other things that could be adjusted to help bring your liver

enzymes back to normal without adjusting the MTX - especially if you were

getting relief from the MTX.

put in the medications that you are taking and it will tell you if there is a

drug interaction to be concerned about. Some of mine have been flagged, but I

know from my Rheumy and Pharmacist that certain risks are minimal in the whole

scheme of things.

Hope this helps. Keep us posted.....Doreen

>

> Mtx seems to be on everyones minds these days. im having a problem

> I was on the pills which upset the tummy, switched to injections

> and they were working better for me was increased on dosage which

> was working even better I was starting to be able to walk up a few

> steps slowly which is a great accomplishment and deal a tad better

> with things well had labwork done and my liver is being notty! Lol

> meaning that my liver levels are too high, I am bloated from it and

> itchy etc, so rheumy said we have to drop my dosage of mtx down and

> added chloroquine and mobic to help the mobic is taking the place

> of lodine which was crap for me. Have any of you taken chloroquine

> or mobic? Thank you for your input, hope you all have a pain free

> weekend.

> **~Dawn~**

> " With GOD all things are possible "

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