REVIEW - Lyprinol - is it a useful anti-inflammatory agent?

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Evid Based Complement Alternat Med. 2009 Apr 21. [Epub ahead of print]

Lyprinol--is it a Useful Anti-inflammatory Agent?

Doggrell SA.

Abstract

The New Zealand green lipped mussel preparation Lyprinol is available

without a prescription from a supermarket, pharmacy or Web. The Food

and Drug Administration have recently warned Lyprinol USA about their

extravagant anti-inflammatory claims for Lyprinol appearing on the

web. These claims are put to thorough review. Lyprinol does have

anti-inflammatory mechanisms, and has anti-inflammatory effects in

some animal models of inflammation. Lyprinol may have benefits in dogs

with arthritis. There are design problems with the clinical trials of

Lyprinol in humans as an anti-inflammatory agent in osteoarthritis and

rheumatoid arthritis, making it difficult to give a definite answer to

how effective Lyprinol is in these conditions, but any benefit is

small. Lyprinol also has a small benefit in atopic allergy. As

anti-inflammatory agents, there is little to choose between Lyprinol

and fish oil. No adverse effects have been reported with Lyprinol.

Thus, although it is difficult to conclude whether Lyprinol does much

good, it can be concluded that Lyprinol probably does no major harm.

PMID: 19383840

http://www.ncbi.nlm.nih.gov/pubmed/19383840

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