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Hello everyone. While I've been reading your posts for a while now, I've only

written on occasion to offer what I hope are helpful insights based on my

experiences.

I've been struggling with RA for 10+ years - diagosed after the birth of my

daughter in 1998. I have had much support and have what I feel is the one of

the best Rheumatologists in my area. This disease is a tough one.

I have recently gone back on methotrexate. I am injecting 10 mgs per week. I

tried it several years ago and could not tolerate it due to nausea and basically

feeling terrible. A specialist in Boston put me on Kytril one hour prior to

taking the medicine and 8 hours after taking the medicine and it definitely

helps.

I'm hoping to combine it with a biologic (all of which I've tried before) to see

if the combination will be the key to success.

I have a question though. Has anyone on methotrexate have difficulty with

muscle and joint pain after taking it? I'm finding that within 24 hours of

taking it, I have joint pain that travels for example from one shoulder to the

other and muscle achiness in the larger muscles of my body. It doesn't last -

it's over in 24-48 hours but I've never experienced this before. I have also

developed lower back pain which is new since the methotrexate.

Has anyone ever experienced these types of symptoms?

Thanks for any information you can share.

Best,

Lenae

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