Guest guest Posted February 3, 2010 Report Share Posted February 3, 2010 Of course get on those prenatals too. You want to be on them for at least 6w prior to conception. I dunno if this has anything to do with RA, like hypothryroidism, this weird trait of MTHFR might be in the genetic soup that is associated with autoimmune diseases. I defer to on that. If you are homozygous for MTHFR you have problems with metabolizing folic acid and can have mc problems. I have one copy, heterozygous, and that is poorly understood when it comes to pg outcomes. To play it safe, my repro endo put me on 1000mg of folic acid/day rather than the traditional 400mg. MTHFR mutation is most often seen in N European, particularly Irish, peoples I believe. I'm suspicious that it all swirls together since I have lots of odd endo/autoimmune issues from the Irish side of my family. I agree with Steph that a good OB will know how long the mtx needs to be out of your system. Since it's a class X drug, you want to be very careful that it's long gone before baby is onboard. I moved right after getting pg and found not all rhuems were thrilled about biologics and pg. One rheum told me to go off Enbrel and increase the pred. I didn't want to do that. I have PCOS and already am prone to weight gain, my first baby was big, and I have relatives with diabetes. I thought increasing pred could lead to problems with gestational diabetes and just plain be unpleasant. I read the papers provided by OTIS and even did some phone counseling with them about Enbrel in pg. They are great, you can call them up if you're having a nervous moment and they'll talk you thru the research findings. I did meet with two rheums who were positive about staying with Enbrel and that's who I worked with. I found that I needed Enbrel less as the pregnancy progressed. I think in my 3rd trimester I was taking it every 2-3 weeks. I had some mild flaring after baby came and my rheum prescribed a burst of pred that was really helpful and got things quieted right down. Also if you can find a pool, lap swimming or kicking around on a kickboard is magical when you're pregnant. You have less swelling, it's gentle exercise, and it's great to keep RA tamed. I swam the night before Charlie was born, although I think I traumatized the teenage girls changing next to me in the locker room. And for anyone having difficulty getting pg, considering talking to your OB about adding metformin. Although it's been found to work with PCOS-related infertility, I have an endo friend who says he recommends it to women who have unexplained infertility. He feels like it irons out some hormone issues that might be hard to detect. I suggested it to an OB working with a woman I see for counseling and it did the trick. Hooray! Keep us posted! Babies are such fun! Kate F Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 3, 2010 Report Share Posted February 3, 2010 Thank you Melynda and , and eveyone else who have given me tips and suggestionsm, keep um coming Thank you Quote Link to comment Share on other sites More sharing options...
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