INFO - The rheumatoid nodule - histology

[Guest guest]

s Hopkins Arthritis

Histology

The rheumatoid nodule is composed of three histologic zones:

Outer zone of vessels, lymphocytes and plasma cells

Middle zone of monocytes migrating from outer zone blood vessels to

the inner zone, with the phenotype changing to activated macrophages

as they travel. These cells are arranged in a typical palisading layer

Inner zone of central necrosis composed of fibrinoid material,

collagen, reticulin fibers, cellular organelles, serum proteins.

http://www.hopkins-arthritis.org/physician-corner/case-rounds/case6/6_case.html

Not an MD

[Guest guest]

I had nodules on my elbows, but sometime after I started Enbrel, they

disappeared. I was glad to see them go!

Sue

On Jan 4, 2009, at 12:45 PM, wrote:

>

> The rheumatoid nodule is composed of three histologic zones:

>

[Guest guest]

Sue and grou;

If RA isn't bad enough, I hear all these others things that come

with it. Well at least if it happens to me I will know what it is.

Thanks so much

gentle hugs

Clora

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> I had nodules on my elbows, but sometime after I started Enbrel,

they

> disappeared. I was glad to see them go!

>

> Sue

>

> On Jan 4, 2009, at 12:45 PM, wrote:

> >

> > The rheumatoid nodule is composed of three histologic zones:

> >

>