RESEARCH - Discovery of process found to play role in RA could lead to new treatment

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MedicalNewsToday.com

Article Date: 30 Jan 2009 - 3:00 PST

Discovery Of Process Found To Play Role In Rheumatoid Arthritis Could

Lead To New Treatment

Although the origin of rheumatoid arthritis (RA) remains unclear,

bioactive proteins known as cytokines, particularly TNFá and IL-6,

which are involved in inflammation, play a major role in the disease

by contributing to joint and tissue destruction. Placenta growth

factor (PIGF), another cytokine, has been thought to be critical for a

new blood vessel formation in the placenta to sufficiently deliver

oxygen and nutrients to fetus. A new study examined the effects of

PIGF on the inflammatory process of RA. The results suggest that PIGF

may play an important role in inflammation in RA joints. The study was

published in the February issue of Arthritis & Rheumatism.

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http://www.medicalnewstoday.com/articles/137302.php

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