Guest guest Posted June 2, 2010 Report Share Posted June 2, 2010 Wish I had better news. I can not take meds due to liver function tests. Developed bleeding ulcers and diabetes due to celebrex....prednison...2.5 mg  I now take gambentin...grin and bear it. I hope you have better luck. Raniolo From: tammy <tcompare@...> Subject: [ ] High Liver function Levels Date: Wednesday, June 2, 2010, 5:01 PM  I am having a hard time getting my LFT's to be within the normal range. This has been going on since Oct of last year so I have not been able to take any meds since then. I have my celebrex and recently prednisone but thats it . I have been off my methotrexate and cannot have any other biological or Dmard because of my LFT's. Now I have to see a liver specialist to see what is going on. Anyone else have a similar experience and what do you do? I am hurting, the prednisone helps but I am scared to be on it and my GP is worried it may cause diabetes??? anyone help? I only take 5 mgs a day to get by so I would appreciate any advice from anyone in a similar situation.... Tammy, Stoney Creek, Ontrio, Canada Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 2, 2010 Report Share Posted June 2, 2010 Hi Tammy, I've had elevated LFTs several times over the years. We've pinned it on: my statin, diflucan, and flexeril in the past. Have you been taking any non RA meds (even Tylenol can do it) that might be contributing? Kate F Sent from my iPhone On Jun 2, 2010, at 4:01 PM, " tammy " <tcompare@...> wrote: I am having a hard time getting my LFT's to be within the normal range. This has been going on since Oct of last year so I have not been able to take any meds since then. I have my celebrex and recently prednisone but thats it . I have been off my methotrexate and cannot have any other biological or Dmard because of my LFT's. Now I have to see a liver specialist to see what is going on. Anyone else have a similar experience and what do you do? I am hurting, the prednisone helps but I am scared to be on it and my GP is worried it may cause diabetes??? anyone help? I only take 5 mgs a day to get by so I would appreciate any advice from anyone in a similar situation.... Tammy, Stoney Creek, Ontrio, Canada Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 3, 2010 Report Share Posted June 3, 2010 Due to the Mtx, my liver functions were off the charts, so Im no longer able to take Mtx or anything like it which means we (my Rheumy and I) cant treat my RA as aggressively as he would like, right now im on enbrel and 5mg prednisone. Good Luck Michele Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 3, 2010 Report Share Posted June 3, 2010 I'm going through the same thing right now - so I surely do understand!! I had taken plaquenil for 2 years with good results, then for some reason the RA decided to speed up, and my hands got a lot worse. Doc doubled the plaquenil, no better, tried mtx ten the problem with the liver tests. Now I've been off the mts for about 6 weeks, still take the plaq, taking 8mg prednisone a day, and no improvement in the liver. (He says it's not cooperating!) I go for a liver ultrasound in 2 weeks to see if something else is going on. Meanwhile.... he also tested another enzyme - I forget the name - to see if I could take another med. I don't want to stay on the pred, altho it has made a BIG difference! I told him we HAVE to do something! How frustrating this disease is!! Roselyn > > I am having a hard time getting my LFT's to be within the normal range. This has been going on since Oct of last year so I have not been able to take any meds since then. I have my celebrex and recently prednisone but thats it . I have been off my methotrexate and cannot have any other biological or Dmard because of my LFT's. Now I have to see a liver specialist to see what is going on. Anyone else have a similar experience and what do you do? I am hurting, the prednisone helps but I am scared to be on it and my GP is worried it may cause diabetes??? anyone help? I only take 5 mgs a day to get by so I would appreciate any advice from anyone in a similar situation.... > > > Tammy, Stoney Creek, > Ontrio, Canada > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 3, 2010 Report Share Posted June 3, 2010 Tammy, It is possible for Celebrex (celecoxib) to cause serious liver toxicity. I hope you can get an answer soon and resume effective treatment. Not an MD On Wed, Jun 2, 2010 at 4:01 PM, tammy <tcompare@...> wrote: > I am having a hard time getting my LFT's to be within the normal range. This has been going on since Oct of last year so I have not been able to take any meds since then. I have my celebrex and recently prednisone but thats it . I have been off my methotrexate and cannot have any other biological or Dmard because of my LFT's. Now I have to see a liver specialist to see what is going on. Anyone else have a similar experience and what do you do? I am hurting, the prednisone helps but I am scared to be on it and my GP is worried it may cause diabetes??? anyone help? I only take 5 mgs a day to get by so I would appreciate any advice from anyone in a similar situation.... > > > Tammy, Stoney Creek, > Ontrio, Canada Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 8, 2010 Report Share Posted June 8, 2010 Tammy, I have heard that Milk Thistle supplements help to " clean " the liver. You might try it. Best of luck to you. Hope you find out what's going on.          Amy From: tammy <tcompare@...> Subject: [ ] High Liver function Levels Date: Wednesday, June 2, 2010, 3:01 PM  I am having a hard time getting my LFT's to be within the normal range. This has been going on since Oct of last year so I have not been able to take any meds since then. I have my celebrex and recently prednisone but thats it . I have been off my methotrexate and cannot have any other biological or Dmard because of my LFT's. Now I have to see a liver specialist to see what is going on. Anyone else have a similar experience and what do you do? I am hurting, the prednisone helps but I am scared to be on it and my GP is worried it may cause diabetes??? anyone help? I only take 5 mgs a day to get by so I would appreciate any advice from anyone in a similar situation.... Tammy, Stoney Creek, Ontrio, Canada Quote Link to comment Share on other sites More sharing options...
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