NEWS - Stomach drugs need movement disorder warning

[Guest guest]

Stomach drugs need movement disorder warning

Thu Feb 26, 2009 6:07pm EST

WASHINGTON, Feb 26 (Reuters) - A class of drugs to treat stomach

disorders needs a strong warning about the risk of involuntary,

repetitive movement on several parts of the body seen with long-term

use or high doses, U.S. regulators said on Thursday.

The drugs contain the ingredient metoclopramide and are available in

various forms including tablets, syrups and injections, the Food and

Drug Administration said. Makers include Baxter International Inc

(BAX.N) and several generic drug companies.

More than 2 million Americans use the medicines to treat

gastroesophageal reflux disease and other stomach ailments, the FDA

said.

Chronic use has been linked to tardive dyskinesia, which causes

repetitive movements of the limbs, lip smacking, grimacing, tongue

protrusion and rapid eye movements and blinking. The symptoms are

rarely reversible but may lessen or resolve after metoclopramide

treatment ends, the FDA said.

The agency ordered manufacturers to add a " black box " warning, the

strongest available, and develop a patient-friendly guide explaining

the risk.

***************************************

Read the entire article here:

http://www.reuters.com/article/companyNews/idUSN2629346520090226

Not an MD

[Guest guest]

I took Reglan to increase my milk production after I had Charlie. They make a

big deal out of watching for signs of depression. They didn't warn me that it

can make you anxious too. I ended up feeling ill at ease, didn't realize it was

the drug, and took a 3rd daily dose. I ended up pacing, crying, wringing my

hands . . . it was awful. I always cringe when I hear how it's given to babies.

Those poor things, no one would know if they were reaction as I did. It might

be a good drug for some people, but for me it was just a terrible experience.

Kate F

________________________________

From: <Rheumatoid.Arthritis.Support@...>

< >

Sent: Saturday, February 28, 2009 9:37:12 PM

Subject: [ ] NEWS - Stomach drugs need movement disorder warning

Stomach drugs need movement disorder warning

Thu Feb 26, 2009 6:07pm EST

WASHINGTON, Feb 26 (Reuters) - A class of drugs to treat stomach

disorders needs a strong warning about the risk of involuntary,

repetitive movement on several parts of the body seen with long-term

use or high doses, U.S. regulators said on Thursday.

The drugs contain the ingredient metoclopramide and are available in

various forms including tablets, syrups and injections, the Food and

Drug Administration said. Makers include Baxter International Inc

(BAX.N) and several generic drug companies.

More than 2 million Americans use the medicines to treat

gastroesophageal reflux disease and other stomach ailments, the FDA

said.

Chronic use has been linked to tardive dyskinesia, which causes

repetitive movements of the limbs, lip smacking, grimacing, tongue

protrusion and rapid eye movements and blinking. The symptoms are

rarely reversible but may lessen or resolve after metoclopramide

treatment ends, the FDA said.

The agency ordered manufacturers to add a " black box " warning, the

strongest available, and develop a patient-friendly guide explaining

the risk.

************ ********* ********* *********

Read the entire article here:

http://www.reuters. com/article/ companyNews/ idUSN26293465200 90226

Not an MD

[Guest guest]

,

Which drugs are they referring to?

Thanks,

Elena NJ

[ ] NEWS - Stomach drugs need movement disorder warning

Stomach drugs need movement disorder warning

Thu Feb 26, 2009 6:07pm EST

WASHINGTON, Feb 26 (Reuters) - A class of drugs to treat stomach

disorders needs a strong warning about the risk of involuntary,

repetitive movement on several parts of the body seen with long-term

use or high doses, U.S. regulators said on Thursday.

The drugs contain the ingredient metoclopramide and are available in

various forms including tablets, syrups and injections, the Food and

Drug Administration said. Makers include Baxter International Inc

(BAX.N) and several generic drug companies.

More than 2 million Americans use the medicines to treat

gastroesophageal reflux disease and other stomach ailments, the FDA

said.

Chronic use has been linked to tardive dyskinesia, which causes

repetitive movements of the limbs, lip smacking, grimacing, tongue

protrusion and rapid eye movements and blinking. The symptoms are

rarely reversible but may lessen or resolve after metoclopramide

treatment ends, the FDA said.

The agency ordered manufacturers to add a " black box " warning, the

strongest available, and develop a patient-friendly guide explaining

the risk.

***************************************

Read the entire article here:

http://www.reuters.com/article/companyNews/idUSN2629346520090226

Not an MD

[Guest guest]

Elena,

They are warning about metoclopramide - that means drugs like Reglan,

Octamide, and Maxolon.

http://www.medicinenet.com/metoclopramide/article.htm

" Metoclopramide is available in a variety of formulations including

tablets, syrups and injections. Names of metoclopramide-containing

products include Reglan Tablets, Reglan Oral Disintegrating Tablets,

Metoclopramide Oral Solution, and Reglan Injection. More than two

million Americans use these products. "

http://www.fda.gov/bbs/topics/NEWS/2009/NEW01963.html

Not an MD

On Sun, Mar 1, 2009 at 6:44 AM, Elena <jubilee07@...> wrote:

> ,

> Which drugs are they referring to?

> Thanks,

> Elena NJ

[Guest guest]

Kate,

That's terrible. I'm sorry you went through that.

A couple of years ago, we had a report from someone in this group who

developed akathisia, possibly permanently. Phenergan (promethazine)

and Wellbutrin (bupropion) were involved.

Not an MD

On Sat, Feb 28, 2009 at 9:42 PM, Fair <kalfoley@...> wrote:

> I took Reglan to increase my milk production after I had Charlie. They make

> a big deal out of watching for signs of depression. They didn't warn me that

> it can make you anxious too. I ended up feeling ill at ease, didn't realize

> it was the drug, and took a 3rd daily dose. I ended up pacing, crying,

> wringing my hands . . . it was awful. I always cringe when I hear how it's

> given to babies. Those poor things, no one would know if they were reaction

> as I did. It might be a good drug for some people, but for me it was just a

> terrible experience. Kate F

[Guest guest]

I was given Reglan many years ago for a hiatel hernia and ended up having a

very rare allergic reaction. I went into a type of static seizure where my

body locked into a very frightening contorted position - my eyes even rolled

back in my head and I couldn't move them. I was in high school at the

time, and I know it must have frightened years off of my parents at the

time. I was rushed to the ER where they had to search out some sort of

antidote. In the meantime, I was totally conscious, even though I couldn't

speak or communicate in any way, so you can imagine my horror when the

nurses put a blanket over my face so that my mom " wouldn't be so upset by

looking at me " !! I must have been an awful site and I guess they thought I

was unconscious. Anyway, they did find an antidote and after some time, it

kicked in and my body started to relax back to a normal state. I have had

no long term effects from it, but I make sure that Reglan is listed in bold

letters with all my other drug allergies!

Ronda

Re: [ ] NEWS - Stomach drugs need movement disorder

warning

Elena,

They are warning about metoclopramide - that means drugs like Reglan,

Octamide, and Maxolon.

http://www.medicine <http://www.medicinenet.com/metoclopramide/article.htm>

net.com/metoclopramide/article.htm

" Metoclopramide is available in a variety of formulations including

tablets, syrups and injections. Names of metoclopramide-containing

products include Reglan Tablets, Reglan Oral Disintegrating Tablets,

Metoclopramide Oral Solution, and Reglan Injection. More than two

million Americans use these products. "

http://www.fda. <http://www.fda.gov/bbs/topics/NEWS/2009/NEW01963.html>

gov/bbs/topics/NEWS/2009/NEW01963.html

Not an MD

On Sun, Mar 1, 2009 at 6:44 AM, Elena <jubilee07comcast (DOT)

<mailto:jubilee07%40comcast.net> net> wrote:

> ,

> Which drugs are they referring to?

> Thanks,

> Elena NJ

[Guest guest]

That's very scary, Ronda. I'm so sorry. I think I'd still be having

nightmares about it.

Not an MD

On Sun, Mar 1, 2009 at 9:54 AM, Ronda <mamaronda@...> wrote:

> I was given Reglan many years ago for a hiatel hernia and ended up having a

> very rare allergic reaction. I went into a type of static seizure where my

> body locked into a very frightening contorted position - my eyes even rolled

> back in my head and I couldn't move them. I was in high school at the

> time, and I know it must have frightened years off of my parents at the

> time. I was rushed to the ER where they had to search out some sort of

> antidote. In the meantime, I was totally conscious, even though I couldn't

> speak or communicate in any way, so you can imagine my horror when the

> nurses put a blanket over my face so that my mom " wouldn't be so upset by

> looking at me " !! I must have been an awful site and I guess they thought I

> was unconscious. Anyway, they did find an antidote and after some time, it

> kicked in and my body started to relax back to a normal state. I have had

> no long term effects from it, but I make sure that Reglan is listed in bold

> letters with all my other drug allergies!

>

> Ronda