Guest guest Posted June 23, 2010 Report Share Posted June 23, 2010 eMedicine.com Last updated 20 Oct 2009 " Urinary Incontinence " Excerpt: Pharmacologic causes Many medications directly or indirectly contribute to urinary incontinence. They must always be considered as the cause of new-onset urinary incontinence, especially in elderly persons where polypharmacy is often encountered.13,14 •Medications with anticholinergic properties or side effects including antipsychotics and antidepressants can cause urinary retention and thus overflow incontinence. •Alpha-adrenergic agonists can cause urinary retention and thus overflow urinary incontinence. •Alpha-antagonist cause urethral relaxation and thus urinary incontinence. •Diuretics can overwhelm bladder capacity causing urinary incontinence in elderly persons. •Calcium channel blockers decrease smooth muscle contractility in the bladder causing urinary retention with overflow incontinence. •Sedative-hypnotics can cause functional urinary incontinence by causing immobility secondary to sedation. •ACE inhibitors can exacerbate urinary incontinence by effects of diuresis as well as side effect of cough with relaxation of pelvic floor musculature. •Anti-parkinson medications can cause urinary urgency and constipation. http://emedicine.medscape.com/article/778772-overview Not an MD Quote Link to comment Share on other sites More sharing options...
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