Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 J Rheumatol. 2009 Mar 13. Plasma 25,OH Vitamin D Concentrations Are Not Associated with Rheumatoid Arthritis (RA)-related Autoantibodies in Individuals at Elevated Risk for RA. Feser M, Derber LA, Deane KD, Lezotte DC, Weisman MH, Buckner JH, Mikuls T, O'Dell J, Gregersen PK, Holers VM, Norris JM. From the Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Denver, Colorado; Division of Rheumatology, Department of Medicine, University of Colorado Denver, Aurora, Colorado; Department of Biostatistics, Colorado School of Public Health, University of Colorado Denver, Denver, Colorado; Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California; Translational Research Program, Benaroya Research Institute, Seattle, Washington; Section of Rheumatology and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska; and the Feinstein Institute for Medical Research, Manhasset, New York, USA. OBJECTIVE: To evaluate the association between rheumatoid arthritis (RA)-related autoantibodies and plasma 25,OH vitamin D in subjects at risk for RA. METHODS: In 1210 subjects without RA, 76 were positive for anti-cyclic citrullinated peptide antibodies or for at least 2 rheumatoid factors (RF; by nephelometry: RF-IgM, RF-IgG, RF-IgA). 25,OH vitamin D was measured in these cases and 154 autoantibody-negative controls from this cohort. RESULTS: 25,OH vitamin D levels did not differ between cases and controls (adjusted OR 1.23, 95% CI 0.93-1.63). C ONCLUSION: Vitamin D concentrations are not associated with RA-related autoimmunity in unaffected subjects at increased risk for RA. PMID: 19286844 http://www.ncbi.nlm.nih.gov/pubmed/19286844 Not an MD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 27, 2009 Report Share Posted March 27, 2009 Interesting article, . That shoots a big hole in another " theory " I heard about on one of those infomercials when they said that correcting a Vitamin D deficiency would help with " arthritis " . People really need to be careful and beware. There are so many " snake oil salesmen " out there who are only looking to make a quick buck by touting " miraculous " results with their products that are aimed at difficult to treat diseases.....Doreen > > J Rheumatol. 2009 Mar 13. > > > Plasma 25,OH Vitamin D Concentrations Are Not Associated with > Rheumatoid Arthritis (RA)-related Autoantibodies in Individuals at > Elevated Risk for RA. > > > Feser M, Derber LA, Deane KD, Lezotte DC, Weisman MH, Buckner JH, > Mikuls T, O'Dell J, Gregersen PK, Holers VM, Norris JM. > > From the Department of Epidemiology, Colorado School of Public > Health, University of Colorado Denver, Denver, Colorado; Division of > Rheumatology, Department of Medicine, University of Colorado Denver, > Aurora, Colorado; Department of Biostatistics, Colorado School of > Public Health, University of Colorado Denver, Denver, Colorado; > Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, > California; Translational Research Program, Benaroya Research > Institute, Seattle, Washington; Section of Rheumatology and > Immunology, Department of Internal Medicine, University of Nebraska > Medical Center, Omaha, Nebraska; and the Feinstein Institute for > Medical Research, Manhasset, New York, USA. > > > OBJECTIVE: To evaluate the association between rheumatoid arthritis > (RA)-related autoantibodies and plasma 25,OH vitamin D in subjects > at risk for RA. > > METHODS: In 1210 subjects without RA, 76 were positive for > anti-cyclic citrullinated peptide antibodies or for at least 2 > rheumatoid factors (RF; by nephelometry: RF-IgM, RF-IgG, RF-IgA). > 25,OH vitamin D was measured in these cases and 154 autoantibody- < negative controls from this cohort. > > RESULTS: 25,OH vitamin D levels did not differ between cases and > controls (adjusted OR 1.23, 95% CI 0.93-1.63). C > > CONCLUSION: Vitamin D concentrations are not associated with > RA-related autoimmunity in unaffected subjects at increased risk > for RA. > > > PMID: 19286844 > > http://www.ncbi.nlm.nih.gov/pubmed/19286844 > > > > Not an MD > Quote Link to comment Share on other sites More sharing options...
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