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Hi All,

I have just come on board tonight so please bare with me while I find my

way around. I'll introduce myself first.

My name is , I am 54 and have had this horrible disease for 12

years now. For the first 5-6 years I managed to continue working as a

nurse/manager of a Nursing Home for the elderly, which I absolutely

adored. About 6 years ago I had a really bad flare up and had to be

hospitalised for the first time. For the first 6 years I was only on MXT

22mg,then it ceased to work. I have had long periods confined to a

wheelchair since then, have bad deformities in both hands and both feet,

and have it in both shoulders, knees,wrists, in fact all over. I badly

need 2 knee replacements, but have been told I'm too young!!!!! That's

strange, because I feel 80 years old.

My Rheumatologist, decided to put me on

Sulphasalazine,Leflunomide,Dihydracodeine,Etoricoxib,Amitriptyline,Omepr\

azole and Paracetamol 6 years ago and I'm still on them now(they have

now ceased to work). After a lot of kicking and screaming, I was finally

given Humira last year, but after 5 injections, I became much worse and

my B.P. went through the roof. He wanted me to go on Enbrel

immediately, but I said no and that I wanted my body to get rid of the

drug before I put anything else in it.

So last friday(13March 09) I had my first injection of Enbrel 50mg, my

next one being this friday. Up til now, I feel no different,but it's

early days.

Has anyone been on this drug for any length of time and seen a marked

improvement? I know it won't change my hands or feet or even my knees.

Think I'm just hoping that I will just feel well, that would be a start.

I have a lovely saint of a husband, who has gone through all this with

me, 2 sons, one of them is currently serving in Afghanistan, the other

who takes me wherever I need to go, and a gorgeous 5 year old

grandaughter who keeps me sane and gives me the reason to keep fighting.

Thank you for allowing me this rant, and I hope to hear from some of you

soon.

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