RESEARCH - Uric acid a key factor in renal dysfunction in RA

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Uric Acid a Key Factor in Renal Dysfunction in RA: Study

NEW YORK (Reuters Health) Aug 07 - In patients with rheumatoid

arthritis (RA), uric acid is a powerful independent predictor of renal

dysfunction and may have a pathogenic role in its development, a study

from the UK suggests.

Uric acid's " potential pathogenic role and clinical use as an early

biomarker of future renal dysfunction in this group of patients need

to be investigated in prospective studies designed specifically for

the purpose, " Dr. Dimitrios Daoussis from the Dudley Group of

Hospitals NHS Trust noted in an email to Reuters Health.

In 350 consecutive patients with RA, Dr. Daoussis and colleagues

investigated whether uric acid is associated with renal dysfunction

and whether such an association is independent or mediated through

other co-morbidities or risk factors for renal impairment.

The investigators assessed and recorded risk factors for renal

dysfunction and measured renal function by glomerular filtration rate

(GFR).

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Read the full article here:

http://www.medscape.com/viewarticle/707197

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