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Hi DD - I'm sorry to hear you are having such a tough time of things. This RA is

definitely a force to be reckoned with. Has your Rheumy mentioned MTX

injections? I switched to that from the pills and the fatigue only lasts one day

instead of three and no more stomach upset because it bypasses the digestive

system altogether. I've not tried any of the other meds you mentioned, although

I did look up the Imuran and the first side effect listed is nausea.

Keep us posted. We care. Praying for pain free days.....Doreen :)

>

> I was diagnosed about a year and a half ago. My RA doc started with

> 30 mg of prednisone, which was like a miracle for me. I went from

> not being able to walk or get up from a chair (toilet) to being

> able to teach my line dance class in just a few hours. I was on

> this for three weeks until I went back for the Dx. He said the

> tests showed I had RA and that my insurance company wanted me to

> start with Methotrexate. I started with 8 pills, which I took every

> Monday morning. I felt sick most of the week. So we cut down and

> he added Arava. That also felt awful and I lost my hair.

>

> So I was able to try Remicade. I'm at the lowest dose in my

> infusions. So I was still on 3 Mtx tablets each Monday. I would

> feel sick on Tuesday, have trouble thinking until usually

> Wednesday. I accredited this to the Mtx. Although I often felt

> fatigued and nauseated on Sunday, which didn't make sense.

>

> So the last time I went, he thought I should try a different drug.

> He started me on a small dose of Imuran and I stopped the Mtx. I

> think he chose Imuran because I also have Crohn's and am having

> some GI issues. I'm losing some of my hair again with the Imuran,

> plus gaining weight, which may not be related to that.

>

> I think I've been on the Imuran for a little over two weeks. There

> have been two Mondays that I have not taken Mtx. But I still have

> the fatigue and nausea, starting Sunday and lasting until late

> Tuesday. I take the Imuran every day, so it's a mystery to me.

>

> Do you have cycles of fatigue and nausea? Can you tell what

> causes it?

>

> dd

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I take 4 tablets now of the methotrexate and after taking it on Thursday

morning ever since after about an hour I have felt nauseaus and fatigued. I

just want to sleep and drink fluids. I have been on a flare up for almost a

month now. I can't just walk into my RA Drs. office without having to pay

$25 due to I owe a balance there. I have taken tylenol extra-strength since

Friday and it helps along with the darvocet with pain. I see my RA Dr. next

week am trying to wait until then to see him.

Irish

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Hey Irish, can I make a small recommendation? Try taking your mtx at night.

You may still feel a slight headache & some nausea, but if taking at night,

you will sleep through some of it. I was always told to take it at night &

have been on it for about 22 years. Hope you get to feeling better. It sure

isn't any fun. Nae

Re: [ ] Mystery

>I take 4 tablets now of the methotrexate and after taking it on Thursday

> morning ever since after about an hour I have felt nauseaus and fatigued.

> I

> just want to sleep and drink fluids. I have been on a flare up for almost

> a

> month now. I can't just walk into my RA Drs. office without having to pay

> $25 due to I owe a balance there. I have taken tylenol extra-strength

> since

> Friday and it helps along with the darvocet with pain. I see my RA Dr.

> next

> week am trying to wait until then to see him.

>

> Irish

>

>

>

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I sure hope it does. I should know better. But this last week, after I'd

been off any RA drugs for about 3 weeks, I took my mtx in the morning

thinking I'd get a jump on things b/c I would be taking Enbrel the next day,

and boy did I pay for it. About 2 hours later, my head felt like a 2-ton

tanker had run over it! And nausea also. Thank goodness, the doc gives me

something to keep on hand for both. That's why I sorta interjected a

recommendation. It was from experience =) Nae

Re: [ ] Mystery

> Thanks. I am going to try this Thursday and hope this does help.

>

> Irish

>

>

>

>

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