INFO - On leucovorin (folinic acid)

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LEDERLE LEUCOVORIN® CALCIUM

Wyeth-Ayerst

Citrovorum Factor

Folic Acid Derivative

Action And Clinical Pharmacology:

Lederle Leucovorin Calcium (calcium folinate), the calcium salt of

folinic acid (citrovorum factor), is a mixture of the diastereoisomers

of the 5-formyl derivative of tetrahydrofolic acid. The biologically

active compound of the mixture is the (-)-L-isomer. It is a metabolite

of folic acid and an essential coenzyme for nucleic acid synthesis.

Leucovorin is a reduced form of folic acid, which is readily converted

to other reduced folic acid derivatives (e.g., tetrahydrofolate).

http://www.rxmed.com/b.main/b2.pharmaceutical/b2.1.monographs/CPS-%20Monographs/\

CPS-%20(General%20Monographs-%20L)/LEDERLE%20LEUCOVORIN.html

Not an MD