INFO - Cushing's help and support

[Guest guest]

Cushing's Help and Support

http://www.cushings-help.com

Excerpt:

The Cortisol Production Pathway

In order to understand how Cushing’s syndrome arises, it is necessary

to briefly examine the cortisol pathway. First, the hypothalamus

secretes corticotropin releasing hormone (CRH). CRH stimulates the

pituitary gland to secrete ACTH, which causes the adrenal glands to

release cortisol into the bloodstream. A biologic feedback loop exists

in which the hypothalamus and pituitary release less CRH and ACTH when

cortisol reaches adequate levels in the bloodstream. However, there

are a number of situations that may upset the cortisol feedback loop,

leading to excess cortisol secretion, and hence, Cushing’s syndrome.

http://www.cushings-help.com/syndrome.htm

Not an MD

[Guest guest]

,

Is there a link between Cushings and RA?

in So Cal

>

> From: Rheumatoid.Arthritis.Support@...

> Date: Wed, 4 Aug 2010 21:16:19 -0500

> Subject: [ ] INFO - Cushing's help and support

>

> Cushing's Help and Support

>

>

> http://www.cushings-help.com

>

>

>

> Excerpt:

>

>

> The Cortisol Production Pathway

>

> In order to understand how Cushing’s syndrome arises, it is necessary

> to briefly examine the cortisol pathway. First, the hypothalamus

> secretes corticotropin releasing hormone (CRH). CRH stimulates the

> pituitary gland to secrete ACTH, which causes the adrenal glands to

> release cortisol into the bloodstream. A biologic feedback loop exists

> in which the hypothalamus and pituitary release less CRH and ACTH when

> cortisol reaches adequate levels in the bloodstream. However, there

> are a number of situations that may upset the cortisol feedback loop,

> leading to excess cortisol secretion, and hence, Cushing’s syndrome.

>

>

> http://www.cushings-help.com/syndrome.htm

>

>

>

>

> Not an MD

>

>

> ------------------------------------

>

>

[Guest guest]

Hello, . The most common link between Cushing's syndrome and RA

is that people who are on prednisone for RA can develop Cushing's or

Cushing's-like symptoms.

But there are some interesting case reports in the literature like this one:

http://www.ncbi.nlm.nih.gov/pubmed/1560610

Not an MD

On Wed, Aug 4, 2010 at 10:23 PM, <islandsusan@...> wrote:

>

> ,

> Is there a link between Cushings and RA?

> in So Cal

[Guest guest]

,

Thanks for the info. I should have mentioned the reason I asked. I was diagnosed

with RA about 8 years ago and a few years later my daughter developed Cushings.

I was concerned that there was a hereditary issue, but according to the research

I can find that's not the case. She did have asthma as a child and used

prednisone for it.

Thanks again! in So Cal

From: Rheumatoid.Arthritis.Support@...

Date: Thu, 5 Aug 2010 07:12:14 -0500

Subject: Re: [ ] INFO - Cushing's help and support

Hello, . The most common link between Cushing's syndrome and RA

is that people who are on prednisone for RA can develop Cushing's or

Cushing's-like symptoms.

But there are some interesting case reports in the literature like this one:

http://www.ncbi.nlm.nih.gov/pubmed/1560610

Not an MD

[Guest guest]

gina,

 

what are the symptoms of cushings

 

thanks

ann

From: <islandsusan@...>

Subject: RE: [ ] INFO - Cushing's help and support

Date: Wednesday, August 4, 2010, 11:23 PM

,

Is there a link between Cushings and RA?

in So Cal

>

> From: Rheumatoid.Arthritis.Support@...

> Date: Wed, 4 Aug 2010 21:16:19 -0500

> Subject: [ ] INFO - Cushing's help and support

>

> Cushing's Help and Support

>

>

> http://www.cushings-help.com

>

>

>

> Excerpt:

>

>

> The Cortisol Production Pathway

>

> In order to understand how Cushing’s syndrome arises, it is necessary

> to briefly examine the cortisol pathway. First, the hypothalamus

> secretes corticotropin releasing hormone (CRH). CRH stimulates the

> pituitary gland to secrete ACTH, which causes the adrenal glands to

> release cortisol into the bloodstream. A biologic feedback loop exists

> in which the hypothalamus and pituitary release less CRH and ACTH when

> cortisol reaches adequate levels in the bloodstream. However, there

> are a number of situations that may upset the cortisol feedback loop,

> leading to excess cortisol secretion, and hence, Cushing’s syndrome.

>

>

> http://www.cushings-help.com/syndrome.htm

>

>

>

>

> Not an MD

>

>

> ------------------------------------

>

>

[Guest guest]

You're welcome, .

I don't know of a genetic association between the two.

Not an MD

On Thu, Aug 5, 2010 at 10:20 AM, <islandsusan@...> wrote:

>

> ,

> Thanks for the info. I should have mentioned the reason I asked. I was

diagnosed with RA about 8 years ago and a few years later my daughter developed

Cushings. I was concerned that there was a hereditary issue, but according to

the research I can find that's not the case. She did have asthma as a child and

used prednisone for it.

> Thanks again! in So Cal