Guest guest Posted August 14, 2010 Report Share Posted August 14, 2010 OKD, It's generally accepted that folic acid decreases MTX efficacy, but to what extent is still being debated. Some rheumatologists recommend avoiding folic acid on the day MTX is taken. Some people take more than 20 mg of MTX per week. Switching to MTX injections should help (usually much higher bioavailability compared to the oral route). Not an MD On Wed, Aug 11, 2010 at 10:02 AM, cofade_2000 <Cofade_2000@...> wrote: > What does it mean if your C-Reactive Protein Level is still high (11.04) after 8 tabs of MTX weekly, 5 mgs of predni daily, weekly Enbrel shots (I take other meds too, like Folic Acid)? > > Does the folic acid reduce the efficacy of the MTX? Can you take more MTX than 8 tabs weekly? Does this mean the ENBREL is not working enuf? > > ? Any tips. My new rheumy just quit and I thought she wasnt so hot anyways. I told her I was loosing my hair, so she made me go down to 4 MTX pills, after 2 weeks I felt the inflamm go sky high and I put myself back on the 8 MTX a month ago...I go back to her, and asked her to take my blood and see whats up, and I got these results: > > My RDW was 16.1 and the C-Reactive was 11.04 everything else was fairly normal..... > > Now that she quit, she referred me to another Rheumy and I have to start all over again. > > UGH>> > > > OKD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 15, 2010 Report Share Posted August 15, 2010 : Thanks. Do you think the inflamm levels are still to high at 11.8? What about the RDW? I feel better since i was a little anemic. I am also going to not take the folic on MTX day, since I am lready up to 18.5 mg of MTX. Thanks OKD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 15, 2010 Report Share Posted August 15, 2010 What are the reference ranges for the CRP and RDW at your lab, OKD? Not an MD On Sun, Aug 15, 2010 at 2:49 PM, OKD <Cofade_2000@...> wrote: > : > > Thanks. Do you think the inflamm levels are still to high at 11.8? What about the RDW? > > I feel better since i was a little anemic. I am also going to not take the folic on MTX day, since I am lready up to 18.5 mg of MTX. > > Thanks > > OKD > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 16, 2010 Report Share Posted August 16, 2010 CRP range here is 1-3 s normal, so on appearances 11.4 would be high, but I read here someone had 80, so that is really ouch! on the RDW I am not sure, all I know is 16.1 is anemic, so they prescribed folic acid daily instead of lecovorin. I am not taking it on MTX day to see if that makes a diff.... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 17, 2010 Report Share Posted August 17, 2010 OKD, That CRP is high. I hope your new rheumatologist will be a good one, and that you'll be seeing some improvement very soon. Not an MD On Mon, Aug 16, 2010 at 1:01 PM, OKD <Cofade_2000@...> wrote: > CRP range here is 1-3 s normal, so on appearances 11.4 would be high, but I read here someone had 80, so that is really ouch! > > on the RDW I am not sure, all I know is 16.1 is anemic, so they prescribed folic acid daily instead of lecovorin. > > I am not taking it on MTX day to see if that makes a diff.... > Quote Link to comment Share on other sites More sharing options...
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