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Re: enbrel effectiveness

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In a message dated 01/27/2003 4:27:18 PM Eastern Standard Time,

keboice@... writes:

> I'm curious, For those of you who've been on enbrel for over a year,

> has it lost effectiveness?

>

I never had as great experience with Enbrel as some on here. It helped, but

wasn't a miracle. I've been on over 2 years. It still seems to have the

same effectiveness with me as it did in the beginning - which isn't a whole

lot.

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I've been using Enbrel for over 2 years with no loss of effectiveness, knock

wood. I use the big fat dull needles that are supplied with the rx. I also take

a small weekly dosage of Methotrexate.

happy trails - Rob Glover

>

> >please, enjoy the effects of the Enbrel now, it looks to me like it

> >will probably last for most of us for a >year or two, then lose

> >effectiveness! :(

>

> I'm curious, For those of you who've been on enbrel for

> over a year,

> has it lost effectiveness?

> --

> Boice

> Health Education & Promotion

> University of California,

> Phone: (530) 752-6336

> E-mail: keboice@...

> http://healthcenter.ucdavis.edu

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  • 7 years later...

Hi ,

I'm afraid that I can't be much help. Methotrexate caused my white

blood cell count to get too low, and Arava just continued the decline.

I was then put on Enbrel, but it seemed to work well for me very

quickly. I've been on it since March of 2003 with continuing good

results.

We're all different in the way we react to various drugs. There are

plenty of other biologic drugs that your rheumy can try if Enbrel is

not working for you. Often when one biologic fails, another one will

succeed.

I wish you luck. Inform your rheumy about what is going on.

Sue

On Oct 17, 2010, at 12:14 AM, ktandtm wrote:

> Hi I haven't posted in a while but had a question. I started enbrel

> 4 weeks ago. It was wonderful the first 2 weeks. Week 3 the pain

> started getting worse and now I just took my 4th shot yesterday and

> my hands, wrists, elbows and knees are back to the severe pain. I

> have also had fluid on my elbows for 1 year now and was hoping the

> enbrel would cause that to go down but it hasn't.

>

> Has anyone else had this happen? I can't add Methotrexate to it. Its

> a drug I can't take. I had to stop the Arava due to low white blood

> cell counts. I am just frustrated. I have heard of these TNF's not

> working after a period of time but never this fast.

>

> Any info would be great.

>

> Thanks,

>

>

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Hi ~

I've been on MTX for over 2 years now & I have no problem with it, along with

Humira.

Maybe the dose was to high for you to tolerate.

I have no pain at all....just stiffness.

I wish you luck.

Pat

>

> Hi I haven't posted in a while but had a question. I started enbrel 4 weeks

ago. It was wonderful the first 2 weeks. Week 3 the pain started getting worse

and now I just took my 4th shot yesterday and my hands, wrists, elbows and knees

are back to the severe pain. I have also had fluid on my elbows for 1 year now

and was hoping the enbrel would cause that to go down but it hasn't.

>

> Has anyone else had this happen? I can't add Methotrexate to it. Its a drug I

can't take. I had to stop the Arava due to low white blood cell counts. I am

just frustrated. I have heard of these TNF's not working after a period of time

but never this fast.

>

> Any info would be great.

>

> Thanks,

>

>

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Sue,

Thank you for your response. I seen my doc end of next week so we shall see.

>

> > Hi I haven't posted in a while but had a question. I started enbrel

> > 4 weeks ago. It was wonderful the first 2 weeks. Week 3 the pain

> > started getting worse and now I just took my 4th shot yesterday and

> > my hands, wrists, elbows and knees are back to the severe pain. I

> > have also had fluid on my elbows for 1 year now and was hoping the

> > enbrel would cause that to go down but it hasn't.

> >

> > Has anyone else had this happen? I can't add Methotrexate to it. Its

> > a drug I can't take. I had to stop the Arava due to low white blood

> > cell counts. I am just frustrated. I have heard of these TNF's not

> > working after a period of time but never this fast.

> >

> > Any info would be great.

> >

> > Thanks,

> >

> >

>

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Pat,

I couldn't tolerate methotrexate at even 2 pills. We tried it. LOL Oh well.

> >

> > Hi I haven't posted in a while but had a question. I started enbrel 4 weeks

ago. It was wonderful the first 2 weeks. Week 3 the pain started getting worse

and now I just took my 4th shot yesterday and my hands, wrists, elbows and knees

are back to the severe pain. I have also had fluid on my elbows for 1 year now

and was hoping the enbrel would cause that to go down but it hasn't.

> >

> > Has anyone else had this happen? I can't add Methotrexate to it. Its a drug

I can't take. I had to stop the Arava due to low white blood cell counts. I am

just frustrated. I have heard of these TNF's not working after a period of time

but never this fast.

> >

> > Any info would be great.

> >

> > Thanks,

> >

> >

>

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