REVIEW - Emotional, physical, and sexual abuse in fibromyalgia syndrome

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Arthritis Care Res (Hoboken). 2010 Aug 18. [Epub ahead of print]

Emotional, physical and sexual abuse in fibromyalgia syndrome - A

systematic review with meta-analysis.

Häuser W, Kosseva M, Uceyler N, Klose P, Sommer C.

Department of Internal Medicine I, Klinikum Saarbrücken, D-66119

Saarbrücken, Germany.

Abstract

INTRODUCTION: An association of fibromyalgia syndrome (FMS) with

emotional, physical, and sexual abuse had been suggested. Therefore we

systematically assessed these associations.

DATA SOURCES AND EXTRACTION: The databases EMBASE, Google Scholar,

MEDLINE, and PsycINFO (through April 2010) and the reference sections

of original studies were searched for eligible studies. Eligible

studies were cohort or case-control studies which assessed at least

one type of emotional, physical or sexual abuse in childhood or

adulthood in FMS and in controls. Two authors independently extracted

descriptive, quality, and outcome data from included studies.

Methodological quality was assessed by the Newcastle-Ottawa Quality

Assessment Scale. Odds ratios (ORs) and 95% confidence intervals (CIs)

were pooled across studies by using the random-effects model.

Heterogeneity was assessed by I(2) statistics.

RESULTS: The search identified 18 eligible case-control studies with

13 095 subjects. There were significant associations between FMS and

self-reported physical abuse in childhood (OR 2.49; 95% CI 1.81- 3.42;

I(2)=0%; 9 studies) and adulthood (OR 3.07; 95% CI 1.01, 9.39;

I(2)=79%; 3 studies) and sexual abuse in childhood (OR 1.94; 95% CI

1.36 .2.75; I(2) = 20%; 10 studies) and adulthood (OR 2.24 95% CI

1.07- 4.70; I(2)= 64%; 4 studies). Study quality was mostly poor. Low

study quality was associated with higher effect sizes for sexual abuse

in childhood, but not with other effect sizes.

CONCLUSION: The association of FMS with physical and sexual abuse

could be confirmed, but is confounded by study quality.

PMID: 20722042

http://www.ncbi.nlm.nih.gov/pubmed/20722042

Not an MD