Guest guest Posted May 18, 2010 Report Share Posted May 18, 2010 > Hi, just finished a six-month Lupron dose/IMRT salvage radiation -- two > 3-month shots, one last October and one the end of January. As of the > end of April, I should be on the downhill side of the Lupron side > effects. Just wondering from others who have been through this, how long > the effects take to wear off. I've heard from three months to a year! No one can say with certainty how long it will take; each of us is different. But I understand that more than a couple of months would be unusual. There is no good reason why should have suffered SEs. Other than that his medic (a urologist?) either did not know or did not care about them. If there is a next time, refer to these two excellent essays on SEs of ADT and what to do about them: http://www.prostate-cancer.org/education/andind/Guess_TestosteroneSideEffects.ht\ ml or http://tinyurl.com/2ymb8f http://www.prostate-cancer.org/education/sidefx/Strum_ADS.html or http://tinyurl.com/g6fzp Regards, Steve J Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 18, 2010 Report Share Posted May 18, 2010 stephen nowlin wrote: > Hi, just finished a six-month Lupron dose/IMRT salvage > radiation -- two 3-month shots, one last October and one the > end of January. As of the end of April, I should be on the > downhill side of the Lupron side effects. Just wondering from > others who have been through this, how long the effects take to > wear off. I've heard from three months to a year! My understanding is that recovery of normal testosterone levels is inversely related to age and the length of time on the drugs. At age 57 I had a 30 day injection of Lupron followed by a 90 day injection, then no more. In theory, the drug should have lasted about 4 months. After about 5-1/2 months, I began to experience recovery in subjective terms. At around 6 months, my testosterone level tested in the normal range. As Steve J indicated, your mileage may vary. Alan Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 18, 2010 Report Share Posted May 18, 2010 Thanks for the links, Steve. For those who might be facing ADT and concerned about SEs, I can offer that the suggestions in the articles Steve referenced do seem to work. My experience with Lupron SEs have been mild, and I did receive and follow advice from my doc about exercise, etc, to offset them. Three weeks after the drug's lifespan, its primary effect of loss of libido persists, along with some leg muscle and joint soreness, hence my question about how long it takes to wear off. But all in all, being on Lupron, at least for a term of six months, hasn't been so bad.../s > To: ProstateCancerSupport > Date: Tue, 18 May 2010 11:51:15 -0700> Subject: Re: Lupron half-life...> > > > > Hi, just finished a six-month Lupron dose/IMRT salvage radiation -- two> > 3-month shots, one last October and one the end of January. As of the> > end of April, I should be on the downhill side of the Lupron side> > effects. Just wondering from others who have been through this, how long> > the effects take to wear off. I've heard from three months to a year!> > No one can say with certainty how long it will take; each of us > is different. But I understand that more than a couple of months > would be unusual.> > There is no good reason why should have suffered SEs. > Other than that his medic (a urologist?) either did not know or > did not care about them.> > If there is a next time, refer to these two excellent essays on > SEs of ADT and what to do about them:> > http://www.prostate-cancer.org/education/andind/Guess_TestosteroneSideEffects.html> or> http://tinyurl.com/2ymb8f> > http://www.prostate-cancer.org/education/sidefx/Strum_ADS.html> or> http://tinyurl.com/g6fzp> > Regards,> > Steve J> > > > ------------------------------------> > There are just two rules for this group > 1 No Spam > 2 Be kind to others> > Please recognise that Prostate Cancerhas different guises and needs different levels of treatment and in some cases no treatment at all. Some men even with all options offered chose radical options that you would not choose. We only ask that people be informed before choice is made, we cannot and should not tell other members what to do, other than look at other options. > > Try to delete old material that is no longer applying when clicking reply> Try to change the title if the content requires it Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 19, 2010 Report Share Posted May 19, 2010  Good for you, Jim. Those 21 sessions will be over before you know it. My 44 are just a distant memory now, although the last one was only 5 months ago. I'm coming to the conclusion that I allowed the side effects to dominate. I didn't work out, gained weight, used a torn rotator cuff as my excuse, but since I've been going through physical therapy for the shoulder and exercising more, EVERYTHING feels and works better. Folks, the lesson here is DON'T sit around and play "woe is me." None of us asked for this, but we have the ability to heal ourselves. Go for it! Your neighbor on the other side of the Cheddar Curtain, Tom Re: Lupron half-life... stephen nowlin <stephennowlinhotmail> wrote:> Hi, just finished a six-month Lupron dose/IMRT salvage> radiation -- two 3-month shots, one last October and one the> end of January. As of the end of April, I should be on the> downhill side of the Lupron side effects. Just wondering from> others who have been through this, how long the effects take to> wear off. I've heard from three months to a year!My understanding is that recovery of normal testosterone levelsis inversely related to age and the length of time on the drugs.At age 57 I had a 30 day injection of Lupron followed by a 90 dayinjection, then no more. In theory, the drug should have lastedabout 4 months. After about 5-1/2 months, I began to experiencerecovery in subjective terms. At around 6 months, mytestosterone level tested in the normal range.As Steve J indicated, your mileage may vary.Alan Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 19, 2010 Report Share Posted May 19, 2010  Good for you, Jim. Those 21 sessions will be over before you know it. My 44 are just a distant memory now, although the last one was only 5 months ago. I'm coming to the conclusion that I allowed the side effects to dominate. I didn't work out, gained weight, used a torn rotator cuff as my excuse, but since I've been going through physical therapy for the shoulder and exercising more, EVERYTHING feels and works better. Folks, the lesson here is DON'T sit around and play "woe is me." None of us asked for this, but we have the ability to heal ourselves. Go for it! Your neighbor on the other side of the Cheddar Curtain, Tom Re: Lupron half-life... stephen nowlin <stephennowlinhotmail> wrote:> Hi, just finished a six-month Lupron dose/IMRT salvage> radiation -- two 3-month shots, one last October and one the> end of January. As of the end of April, I should be on the> downhill side of the Lupron side effects. Just wondering from> others who have been through this, how long the effects take to> wear off. I've heard from three months to a year!My understanding is that recovery of normal testosterone levelsis inversely related to age and the length of time on the drugs.At age 57 I had a 30 day injection of Lupron followed by a 90 dayinjection, then no more. In theory, the drug should have lastedabout 4 months. After about 5-1/2 months, I began to experiencerecovery in subjective terms. At around 6 months, mytestosterone level tested in the normal range.As Steve J indicated, your mileage may vary.Alan Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 19, 2010 Report Share Posted May 19, 2010 stephen nowlin wrote: > ... its primary effect of loss of libido persists, along with > some leg muscle and joint soreness, hence my question about how > long it takes to wear off. I forgot to say in my posting about this that I started to get stiffness and pain in all of my finger joints and some toe joints about 4-6 month after the end of Lupron treatment. There was also " trigger finger " in some fingers. This grew steadily worse. I tried all the standard anti-inflammatory drugs with no effect. It turned out the solution was massive amounts of exercise for both flexibility and strength. After about a year the problem went completely away. It's hard to prove that this was caused by the Lupron and, if it was, I have no idea why the problem should have only begun well after the end of treatment. But since pain in small joints is very common with Lupron, and since it eventually went completely away (which it wouldn't have done if it were arthritis), I assume that it was caused by the Lupron treatment. Alan Quote Link to comment Share on other sites More sharing options...
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