PTOV1

[Guest guest]

I was wondering if anyone here has heard any more info about PTOV1 as a

gene/protein expression of prostate cancer since the published research in 2008.

I realize PCA3 has been somewhat cast a pall upon by the fact that interthelial

neoplasia also expresses it to a very high level just as cancerous tissue does.

Apparatently, PTOV1 is can distinguish between HGPIN that leads quickly to

cancer versus HGPIN that does not.

I have seen nothing further since that. Presumably, testing for PTOV1 in people

with HGPIN indications in their biopsies would be a more accurate precursor

measure than using PCA3 and would lead to either subsequent testing or a

commercial test by now.

Rich L

[Guest guest]

Rich wrote:

> I was wondering if anyone here has heard any more info about

> PTOV1 as a gene/protein expression of prostate cancer since the

> published research in 2008. I realize PCA3 has been somewhat

> cast a pall upon by the fact that interthelial neoplasia also

> expresses it to a very high level just as cancerous tissue

> does. Apparatently, PTOV1 is can distinguish between HGPIN that

> leads quickly to cancer versus HGPIN that does not.

>

> I have seen nothing further since that. Presumably, testing for

> PTOV1 in people with HGPIN indications in their biopsies would

> be a more accurate precursor measure than using PCA3 and would

> lead to either subsequent testing or a commercial test by now.

Rich,

I don't know the answer to your question but you might try

posting it to the Usenet newsgroup " sci.med.prostate.cancer " .

There's not much activity there but there are some people who are

more knowledgeable about the science than most of us.

Alan