Guest guest Posted February 11, 2010 Report Share Posted February 11, 2010 Dana, Although anything is possible, it seems very unlikely that your PSA level is affected by such activities after surgery, especially as you table a record of steady increases. I regret to say that this is much more likely to indicate what is termed bio-chemical failure. All the best Terry Herbert I have no medical qualifications but I was diagnosed in ‘96: and have learned a bit since then. My sites are at www.yananow.net and www.prostatecancerwatchfulwaiting.co.za Dr “Snuffy” Myers : " As a physician, I am painfully aware that most of the decisions we make with regard to prostate cancer are made with inadequate data " From: ProstateCancerSupport [mailto:ProstateCancerSupport ] On Behalf Of Dana Sent: Friday, 12 February 2010 10:43 AM To: ProstateCancerSupport Subject: PSA Rise I know from the literature that PSA can rise if the patient has sex or rides a bicycle in the day(s) preceding the blood draw. How about if the patient has already had his prostate removed? Can strenuous exercise (like bicycling) cause a rise in PSA? I'm 5+ years since prostate removal. It's been an ordeal all the way. My Gleason is a 9. I've had RP, chemo, salvage radiation, and am on Lupron and Casodex. In the past year, my PSA went from undetectable to 0.1, to 0.2, to o.4, to 0.6, to 0.7. Today I got the latest results. Today my PSA is 1.3. It was 0.7 in November. It struck me that I had ridden the exercise bicycle for 30 minutes the day before my latest blood draw. Without a prostate, could I expect an increase in PSA due to the exercise? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 11, 2010 Report Share Posted February 11, 2010 Thanks Terry. I value your opinion. I was hoping for a different answer, but in my heart, I knew it couldn't be explained away that easily. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 11, 2010 Report Share Posted February 11, 2010 Dana wrote: > Without a prostate, could I expect an increase in PSA due to the exercise? Dana, I'm not an expert but, like Terry, I also have doubts that your exercycle work could be involved in this. Since you've had all of those treatments, I presume that you have a medical oncologist working with you. Does he have anything more up his sleeve? Some drugs I've heard of being used after ADT failure include ketoconazole, estrogen patches, revlimid, and some patients have tried non-prescription aids like pomegranate extract. Some have claimed success with Prostasol, a chinese herbal concoction containing who knows what, formerly sold by a huckster named Donsbach. If I were you, I would look into clinical trials. It sounds like you're quite healthy now, which might make you a very good candidate for trials of Provenge, MDV3100, Abiraterone, or other new treatments. Best of luck. Alan Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 11, 2010 Report Share Posted February 11, 2010 Good advice Alan, thanks. This PSA was with my urologist. I see my oncologist next month and he will do another PSA. He has said he will probably take me off the Casodex as the next step. A downward bounce of the PSA sometimes happens when you remove the Casodex. I'll arm myself with your suggestions when I see him. Thanks, again. > > > > Without a prostate, could I expect an increase in PSA due to the exercise? > > Dana, > > I'm not an expert but, like Terry, I also have doubts that your > exercycle work could be involved in this. > > Since you've had all of those treatments, I presume that you > have a medical oncologist working with you. Does he have > anything more up his sleeve? Some drugs I've heard of being > used after ADT failure include ketoconazole, estrogen patches, > revlimid, and some patients have tried non-prescription aids > like pomegranate extract. Some have claimed success with > Prostasol, a chinese herbal concoction containing who knows > what, formerly sold by a huckster named Donsbach. > > If I were you, I would look into clinical trials. It sounds > like you're quite healthy now, which might make you a very good > candidate for trials of Provenge, MDV3100, Abiraterone, or > other new treatments. > > Best of luck. > > Alan > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 11, 2010 Report Share Posted February 11, 2010 From my expirience, if you have a PSA reading, then there is a bit of prostate producing it. I had a radical 10 years ago. My PSA gradually increased to .18, so I had to undergo radiology treatments last September. Surely your urologist will refer you to an oncologist if you PSA reading gets too high. Good luck Re: PSA Rise Dana <dbwilbourn> wrote:> Without a prostate, could I expect an increase in PSA due to the exercise?Dana,I'm not an expert but, like Terry, I also have doubts that yourexercycle work could be involved in this.Since you've had all of those treatments, I presume that you have a medical oncologist working with you. Does he have anything more up his sleeve? Some drugs I've heard of beingused after ADT failure include ketoconazole, estrogen patches,revlimid, and some patients have tried non-prescription aidslike pomegranate extract. Some have claimed success withProstasol, a chinese herbal concoction containing who knowswhat, formerly sold by a huckster named Donsbach.If I were you, I would look into clinical trials. It soundslike you're quite healthy now, which might make you a very goodcandidate for trials of Provenge, MDV3100, Abiraterone, orother new treatments.Best of luck.Alan Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 11, 2010 Report Share Posted February 11, 2010 Riding a bike probably, even after removal of prostate and radiation, will cause some rise in PSA depending where the tumor is located. I would have the PSA checked in a month and see where you are. However, if the psa has indeed risen then this is a serious condition if you are on Lupron and T is at castrate levels. It could mean that your cancer has become HRPCa hormone refractory prostate cancer. Best of luck to you. Steve B PSA Rise I know from the literature that PSA can rise if the patient has sex or rides a bicycle in the day(s) preceding the blood draw. How about if the patient has already had his prostate removed? Can strenuous exercise (like bicycling) cause a rise in PSA? I'm 5+ years since prostate removal. It's been an ordeal all the way. My Gleason is a 9. I've had RP, chemo, salvage radiation, and am on Lupron and Casodex. In the past year, my PSA went from undetectable to 0.1, to 0.2, to o.4, to 0.6, to 0.7. Today I got the latest results. Today my PSA is 1.3. It was 0.7 in November. It struck me that I had ridden the exercise bicycle for 30 minutes the day before my latest blood draw. Without a prostate, could I expect an increase in PSA due to the exercise? ------------------------------------ There are just two rules for this group 1 No Spam 2 Be kind to others Please recognise that Prostate Cancerhas different guises and needs different levels of treatment and in some cases no treatment at all. Some men even with all options offered chose radical options that you would not choose. We only ask that people be informed before choice is made, we cannot and should not tell other members what to do, other than look at other options. Try to delete old material that is no longer applying when clicking reply Try to change the title if the content requires it Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 12, 2010 Report Share Posted February 12, 2010 Thanks, Steve. You can bet that I won't be back on the exercise bike between now and March 15 when I get my next PSA test. > > Riding a bike probably, even after removal of prostate and radiation, will cause some rise in PSA depending where the tumor is located. > > I would have the PSA checked in a month and see where you are. However, if the psa has indeed risen then this is a serious condition if you are on Lupron and T is at castrate levels. It could mean that your cancer has become HRPCa hormone refractory prostate cancer. > > Best of luck to you. > > > Steve B > > > PSA Rise > > I know from the literature that PSA can rise if the patient has sex or rides a bicycle in the day(s) preceding the blood draw. > > How about if the patient has already had his prostate removed? Can strenuous exercise (like bicycling) cause a rise in PSA? > > I'm 5+ years since prostate removal. It's been an ordeal all the way. My Gleason is a 9. I've had RP, chemo, salvage radiation, and am on Lupron and Casodex. In the past year, my PSA went from undetectable to 0.1, to 0.2, to o.4, to 0.6, to 0.7. Today I got the latest results. Today my PSA is 1.3. It was 0.7 in November. > > It struck me that I had ridden the exercise bicycle for 30 minutes the day before my latest blood draw. > > Without a prostate, could I expect an increase in PSA due to the exercise? > > > > ------------------------------------ > > There are just two rules for this group > 1 No Spam > 2 Be kind to others > > Please recognise that Prostate Cancerhas different guises and needs different levels of treatment and in some cases no treatment at all. Some men even with all options offered chose radical options that you would not choose. We only ask that people be informed before choice is made, we cannot and should not tell other members what to do, other than look at other options. > > Try to delete old material that is no longer applying when clicking reply > Try to change the title if the content requires it Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 22, 2010 Report Share Posted November 22, 2010 Metcalf wrote: > Just found out today that my PSA has risen from a steady 53 to > 85 over the last 2 to 3 months. > > I think we might move to Ketoconazole plus hydrocortisone as > the next step, replacing the DES + Clopidogrel > > Best of luck . We'll all be thinking of you. Alan Quote Link to comment Share on other sites More sharing options...
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